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Tmed8 Gene Detail
Summary
  • Symbol
    Tmed8
  • Name
    transmembrane p24 trafficking protein 8
  • Synonyms
    6430595O10Rik, LOC382620, Mem1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923480
    NCBI Gene: 382620
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:87213011-87247228 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 41.36 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1002 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923480
 protein coding gene Chr12:87195547-87247264 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019980
 protein coding gene Chr12:88061579-88096753 (-)
A/J MGP_AJ_G0019938
 protein coding gene Chr12:84716533-84750548 (-)
AKR/J MGP_AKRJ_G0019913
 protein coding gene Chr12:87015495-87049498 (-)
BALB/cJ MGP_BALBcJ_G0019917
 protein coding gene Chr12:85049594-85083544 (-)
C3H/HeJ MGP_C3HHeJ_G0019723
 protein coding gene Chr12:87502454-87538078 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020369
 protein coding gene Chr12:90591044-90630303 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017987
 protein coding gene Chr12:81593465-81628654 (-)
CAST/EiJ MGP_CASTEiJ_G0019273
 protein coding gene Chr12:82524659-82561669 (-)
CBA/J MGP_CBAJ_G0019695
 protein coding gene Chr12:94078901-94112832 (-)
DBA/2J MGP_DBA2J_G0019808
 protein coding gene Chr12:84211067-84245367 (-)
FVB/NJ MGP_FVBNJ_G0019795
 protein coding gene Chr12:83204796-83238587 (-)
LP/J MGP_LPJ_G0019882
 protein coding gene Chr12:87943956-87977984 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019834
 protein coding gene Chr12:96838332-96873381 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020401
 protein coding gene Chr12:86645258-86679264 (-)
PWK/PhJ MGP_PWKPhJ_G0019037
 protein coding gene Chr12:78763549-78797747 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018832
 protein coding gene Chr12:81136504-81181849 (-)
WSB/EiJ MGP_WSBEiJ_G0019326
 protein coding gene Chr12:87420895-87454928 (-)



Homology
more
  • Human Ortholog
    TMED8, transmembrane p24 trafficking protein family member 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMED8, transmembrane p24 trafficking protein family member 8
  • Synonyms
    FAM15B
  • Links
    NCBI Gene ID: 283578
    UniProt: Q6PL24

  • Chr Location
    14q24.3; chr14:77335021-77377094 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    4
  • cDNA Data
    47
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034111 Ensembl Gene Model | MGI Sequence Detail 34218 C57BL/6J ±  kb
transcript ENSMUST00000037418 Ensembl | MGI Sequence Detail 7409 Not Applicable  
polypeptide ENSMUSP00000043742 Ensembl | MGI Sequence Detail 326 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    cDNA 47
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-35772, MGI:107306, MGI:2144824, MGI:2686030
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Phenotypes 9
  • Earliest
    J:37789 Ciciotte SL, et al., Gata2 maps to mouse chromosome 6. Mamm Genome. 1997 Jan;8(1):69-70
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory