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Adhfe1 Gene Detail
Summary
  • Symbol
    Adhfe1
  • Name
    alcohol dehydrogenase, iron containing, 1
  • Synonyms
    6330565B14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923437
    NCBI Gene: 76187
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:9618173-9648195 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 2.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1012 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923437
 protein coding gene Chr1:9618173-9650898 (+)
129S1/SvImJ ENSMUSG00200002157
 protein coding gene Chr1:6934911-6967910 (+)
A/J ENSMUSG00195002641
 protein coding gene Chr1:6757781-6790508 (+)
AKR/J ENSMUSG00220003001
 protein coding gene Chr1:6852968-6885966 (+)
BALB/cJ ENSMUSG00180008939
 protein coding gene Chr1:6841367-6874091 (+)
C3H/HeJ ENSMUSG00175000194
 protein coding gene Chr1:6723535-6756197 (+)
C57BL/6NJ ENSMUSG00215004052
 protein coding gene Chr1:6802552-6835280 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013937
 protein coding gene Chr1:5707880-5739999 (+)
CAST/EiJ ENSTCUG00005001897
 protein coding gene Chr1:7173266-7204503 (+)
CBA/J ENSMUSG00210001553
 protein coding gene Chr1:6583057-6615717 (+)
DBA/2J ENSMUSG00185004109
 protein coding gene Chr1:7679680-7712400 (+)
FVB/NJ ENSMUSG00205005051
 protein coding gene Chr1:6934918-6967644 (+)
JF1/MsJ ENSUMUG00000003457
 protein coding gene Chr1:6964050-6995277 (+)
LP/J ENSMUSG00230002055
 protein coding gene Chr1:7676641-7709637 (+)
NOD/ShiLtJ ENSMUSG00190001023
 protein coding gene Chr1:6729757-6762752 (+)
NZO/HlLtJ ENSMUSG00225005029
 protein coding gene Chr1:11083768-11116490 (+)
PWK/PhJ ENSLUMG00010002229
 protein coding gene Chr1:6565110-6596419 (+)
SPRET/EiJ ENSMSPG00010013409
 protein coding gene Chr1:7169285-7197643 (+)
WSB/EiJ ENSIUOG00005010983
 protein coding gene Chr1:6761108-6793834 (+)



Homology
more
  • Human Ortholog
    ADHFE1, alcohol dehydrogenase iron containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADHFE1, alcohol dehydrogenase iron containing 1
  • Synonyms
    ADH8, HMFT2263, HOT
  • Links
    NCBI Gene ID: 137872
    UniProt: Q8IWW8

  • Chr Location
    8q13.1; chr8:66432467-66468907 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    955
  • Tissues
    117
  • cDNA Data
    63
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76187 NCBI Gene Model | MGI Sequence Detail 30023 C57BL/6J ±  kb
transcript NM_001357377 RefSeq | MGI Sequence Detail 3416 C57BL/6  
polypeptide Q8R0N6 UniProt | EBI | MGI Sequence Detail 465 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 63
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:2138150
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Gene Ontology 10
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory