Vcf2 MGI Mouse Gene Detail - MGI:1923420 - VCP nuclear cofactor family member 2

Symbol

Vcf2
Name

VCP nuclear cofactor family member 2
Synonyms

2700081K05Rik, 6330540D07Rik, Tmem29

Feature Type

protein coding gene
IDs

MGI:1923420
NCBI Gene: 382245
Alliance

genome feature page
Transcription Start Sites

9 TSS

Sequence Map

ChrX:149180769-149242150 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 68.46 cM
Mapping Data

1 experiment

SNPs within 2kb

1048 from dbSNP Build 142
Strain Annotations

31

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1923420	protein coding gene	ChrX:149180769-149250327 (-)
129S1/SvImJ	ENSMUSG00200030210	protein coding gene	ChrX:125976570-125977713 (-)
129S1/SvImJ	ENSMUSG00200030239	protein coding gene	ChrX:125985058-126088168 (-)
A/J	ENSMUSG00195020000	protein coding gene	ChrX:130988815-131092134 (-)
A/J	ENSMUSG00195019981	protein coding gene	ChrX:130980327-130981470 (-)
AKR/J	ENSMUSG00220033220	protein coding gene	ChrX:122993136-123096232 (-)
AKR/J	ENSMUSG00220033173	protein coding gene	ChrX:122984648-122985791 (-)
BALB/cJ	ENSMUSG00180036090	protein coding gene	ChrX:126372606-126373749 (-)
BALB/cJ	ENSMUSG00180036128	protein coding gene	ChrX:126381094-126484408 (-)
C3H/HeJ	ENSMUSG00175028961	protein coding gene	ChrX:130903582-130964654 (-)
C3H/HeJ	ENSMUSG00175028934	protein coding gene	ChrX:130895094-130896237 (-)
C57BL/6NJ	ENSMUSG00215019301	protein coding gene	ChrX:126668637-126771750 (-)
C57BL/6NJ	ENSMUSG00215019272	protein coding gene	ChrX:126660149-126661292 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033483	protein coding gene	ChrX:138905364-138964356 (-)
CAST/EiJ	ENSTCUG00005034094	protein coding gene	ChrX:128705691-128706834 (-)
CBA/J	ENSMUSG00210030421	protein coding gene	ChrX:128372464-128373607 (-)
CBA/J	ENSMUSG00210030441	protein coding gene	ChrX:128380952-128484061 (-)
DBA/2J	ENSMUSG00185041444	protein coding gene	ChrX:143193902-143195045 (-)
DBA/2J	ENSMUSG00185041474	protein coding gene	ChrX:143202390-143263462 (-)
FVB/NJ	ENSMUSG00205015514	protein coding gene	ChrX:126951857-127050051 (-)
FVB/NJ	ENSMUSG00205015490	protein coding gene	ChrX:126943369-126944512 (-)
JF1/MsJ	ENSUMUG00000021858	protein coding gene	ChrX:163424284-163425427 (-)
LP/J	ENSMUSG00230030197	protein coding gene	ChrX:150004594-150107696 (-)
LP/J	ENSMUSG00230030154	protein coding gene	ChrX:149996106-149997249 (-)
NOD/ShiLtJ	ENSMUSG00190036577	protein coding gene	ChrX:127489441-127490584 (-)
NOD/ShiLtJ	ENSMUSG00190036644	protein coding gene	ChrX:127497929-127601232 (-)
NZO/HlLtJ	ENSMUSG00225041504	protein coding gene	ChrX:153493236-153494379 (-)
NZO/HlLtJ	ENSMUSG00225041511	protein coding gene	ChrX:153501724-153563035 (-)
PWK/PhJ	ENSLUMG00010030109	protein coding gene	ChrX:124959328-124960471 (-)
SPRET/EiJ	ENSMSPG00010034843	protein coding gene	ChrX:129801060-129802203 (-)
WSB/EiJ	ENSIUOG00005037399	protein coding gene	ChrX:127960354-127961497 (-)

Human Ortholog

FAM156A, family with sequence similarity 156 member A

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM156A, family with sequence similarity 156 member A
Synonyms

PRO0659, TMEM29
Links

HGNC:30114

NCBI Gene ID: 29057

UniProt: Q8NDB6
Chr Location

Xp11.22

Human Ortholog

FAM156B, family with sequence similarity 156 member B
Synonyms

TMEM29B
Links

HGNC:31962

NCBI Gene ID: 727866

UniProt: Q8NDB6
Chr Location

Xp11.22

MGI Vertebrate Homology

Vcf2 stringent orthology
2 human;1 mouse
HCOP

vertebrate homology predictions: FAM156A, FAM156B
Gene Tree

Vcf2

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Phenotype Summary

6 phenotype references

All Mutations and Alleles

38
Gene trapped

36
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

21 strains or lines available

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All GO Annotations

2
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

43

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

85
RefSeq

20
UniProt

3
CCDS

CCDS53218.1, CCDS53219.1

Ensembl

ENSMUSG00000041353 (Evidence)
NCBI Gene

382245

			Length	Strain/Species	Flank
genomic	ENSMUSG00000041353	Ensembl Gene Model \| MGI Sequence Detail	61382	C57BL/6J	± kb
transcript	ENSMUST00000059256	Ensembl \| MGI Sequence Detail	1402	Not Applicable
polypeptide	ENSMUSP00000053632	Ensembl \| MGI Sequence Detail	204	Not Applicable

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UniProt

3 Sequences
InterPro Domains

IPR029096 Developmental pluripotency-associated protein 3

IPR029222 VCF1/2-like

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All nucleic 43

cDNA 43

Microarray probesets 4

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MGI:1919903, MGI:7529392

Summaries

All 29

Gene Ontology 2

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:317250 Tsang HW, et al., Transmembrane 29 (Tmem29), a Newly Identified Molecule Showed Downregulation in Hypoxic-Ischemic Brain Damage. NeuroSci. 2022;3(1):41-51

TSS for Vcf2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr164361	ChrX:149242124-149242153 (-)	11 bp
Tssr164360	ChrX:149241799-149241804 (-)	348 bp
Tssr164359	ChrX:149240372-149240375 (-)	1,776 bp
Tssr164358	ChrX:149224054-149224065 (-)	18,090 bp
Tssr164357	ChrX:149223883-149223933 (-)	18,242 bp
Tssr164356	ChrX:149223831-149223842 (-)	18,313 bp
Tssr164355	ChrX:149218506-149218537 (-)	23,628 bp
Tssr164354	ChrX:149218478-149218486 (-)	23,668 bp
Tssr164353	ChrX:149198073-149198086 (-)	44,070 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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