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Hdnr Gene Detail
Summary
  • Symbol
    Hdnr
  • Name
    Hand2 downstream lncRNA
  • Synonyms
    5033428I22Rik, Handlr, handsdown, Hdn
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1923246
    NCBI Gene: 75996
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:57785470-57807615 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 29.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923246
 lncRNA gene Chr8:57785152-57832375 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007327
 lincRNA gene Chr8:57044642-57053150 (+)
A/J MGP_AJ_G0007325
 lincRNA gene Chr8:54649906-54658414 (+)
AKR/J MGP_AKRJ_G0007296
 lincRNA gene Chr8:56272511-56281039 (+)
BALB/cJ MGP_BALBcJ_G0007303
 lincRNA gene Chr8:54964587-54973086 (+)
C3H/HeJ MGP_C3HHeJ_G0007246
 lincRNA gene Chr8:56929447-56937943 (+)
C57BL/6NJ MGP_C57BL6NJ_G0007473
 lincRNA gene Chr8:59234688-59245206 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0006671
 lincRNA gene Chr8:50198221-50206810 (+)
CAST/EiJ MGP_CASTEiJ_G0007148
 lincRNA gene Chr8:56298254-56306399 (+)
CBA/J MGP_CBAJ_G0007229
 lincRNA gene Chr8:61344034-61352741 (+)
DBA/2J MGP_DBA2J_G0007251
 lincRNA gene Chr8:54460280-54469207 (+)
FVB/NJ MGP_FVBNJ_G0007272
 lincRNA gene Chr8:53817061-53825592 (+)
LP/J MGP_LPJ_G0007332
 lincRNA gene Chr8:57062659-57071165 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007249
 lincRNA gene Chr8:62957700-62967319 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0007475
 lincRNA gene Chr8:56493403-56501871 (+)
PWK/PhJ MGP_PWKPhJ_G0007090
 lincRNA gene Chr8:53764264-53772900 (+)
SPRET/EiJ MGP_SPRETEiJ_G0006998
 lincRNA gene Chr8:55373264-55382928 (+)
WSB/EiJ MGP_WSBEiJ_G0007208
 lincRNA gene Chr8:56742475-56751094 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit decreased heart left ventricle weight and increased cardiac muscle contractility but exhibit reduced lung hypertrophy following trans-aortic constriction.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    743
  • Tissues
    19
  • cDNA Data
    10
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      61
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75996 NCBI Gene Model | MGI Sequence Detail 22146 C57BL/6J ±  kb
    transcript NR_131041 RefSeq | MGI Sequence Detail 952 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 10
      Primer pair 7
    References
    more
    • Summaries
      All 11
      Developmental Gene Expression 2
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:284183 George MR, et al., Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs. Development. 2019 Dec 9;146(23):dev185314
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory