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Fam227b Gene Detail
Summary
  • Symbol
    Fam227b
  • Name
    family with sequence similarity 227, member B
  • Synonyms
    4930525F21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923073
    NCBI Gene: 75823
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:125825403-125993924 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 61.76 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3219 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923073
 protein coding gene Chr2:125825403-125994048 (-)
129S1/SvImJ ENSMUSG00200044251
 protein coding gene Chr2:122871521-123043691 (-)
A/J ENSMUSG00195030071
 protein coding gene Chr2:122901518-123067743 (-)
AKR/J ENSMUSG00220044796
 protein coding gene Chr2:122660661-122832852 (-)
BALB/cJ ENSMUSG00180046199
 protein coding gene Chr2:122688452-122854669 (-)
C3H/HeJ ENSMUSG00175037708
 protein coding gene Chr2:123189016-123376774 (-)
C57BL/6NJ ENSMUSG00215025946
 protein coding gene Chr2:122746212-122914909 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024234
 protein coding gene Chr2:118717141-118861677 (-)
CAST/EiJ ENSTCUG00005037310
 protein coding gene Chr2:122035212-122199011 (-)
CBA/J ENSMUSG00210029821
 protein coding gene Chr2:123037514-123225309 (-)
DBA/2J ENSMUSG00185032309
 protein coding gene Chr2:122691660-122879441 (-)
FVB/NJ ENSMUSG00205036082
 protein coding gene Chr2:121900000-122069671 (-)
JF1/MsJ ENSUMUG00000007339
 protein coding gene Chr2:122556659-122750399 (-)
LP/J ENSMUSG00230034879
 protein coding gene Chr2:124509971-124682133 (-)
NOD/ShiLtJ ENSMUSG00190012701
 protein coding gene Chr2:122867771-123039943 (-)
NZO/HlLtJ ENSMUSG00225002638
 protein coding gene Chr2:132416106-132588284 (-)
PWK/PhJ ENSLUMG00010038589
 protein coding gene Chr2:122452373-122631892 (-)
SPRET/EiJ ENSMSPG00010030663
 protein coding gene Chr2:124912925-125071941 (-)
WSB/EiJ ENSIUOG00005036465
 protein coding gene Chr2:122680888-122847090 (-)



Homology
more
  • Human Ortholog
    FAM227B, family with sequence similarity 227 member B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM227B, family with sequence similarity 227 member B
  • Synonyms
    C15orf33
  • Links
    NCBI Gene ID: 196951
    UniProt: Q96M60

  • Chr Location
    15q21.2; chr15:49326962-49620929 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027209 Ensembl Gene Model | MGI Sequence Detail 168522 C57BL/6J ±  kb
    transcript ENSMUST00000110446 Ensembl | MGI Sequence Detail 1858 Not Applicable  
    polypeptide ENSMUSP00000106076 Ensembl | MGI Sequence Detail 532 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    References
    more
    • Summaries
      All 30
      Phenotypes 13
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory