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Fam227a Gene Detail
Summary
  • Symbol
    Fam227a
  • Name
    family with sequence similarity 227, member A
  • Synonyms
    4933432B09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922979
    NCBI Gene: 75729
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:79496518-79543157 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.81 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2913 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922979
 protein coding gene Chr15:79493777-79543157 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022079
 protein coding gene Chr15:79897791-79956593 (-)
A/J MGP_AJ_G0022040
 protein coding gene Chr15:77134232-77187848 (-)
AKR/J MGP_AKRJ_G0022015
 protein coding gene Chr15:79293083-79345773 (-)
BALB/cJ MGP_BALBcJ_G0022046
 protein coding gene Chr15:77154206-77203479 (-)
C3H/HeJ MGP_C3HHeJ_G0021817
 protein coding gene Chr15:79284598-79336423 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022489
 protein coding gene Chr15:83043263-83096604 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020019
 protein coding gene Chr15:73614289-73663465 (-)
CAST/EiJ MGP_CASTEiJ_G0021338
 protein coding gene Chr15:79991960-80044330 (-)
CBA/J MGP_CBAJ_G0021782
 protein coding gene Chr15:85627912-85679601 (-)
DBA/2J MGP_DBA2J_G0021911
 protein coding gene Chr15:76625690-76675551 (-)
FVB/NJ MGP_FVBNJ_G0021889
 protein coding gene Chr15:75650242-75700572 (-)
LP/J MGP_LPJ_G0021979
 protein coding gene Chr15:80083956-80143800 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021909
 protein coding gene Chr15:90727679-90780944 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022503
 protein coding gene Chr15:79309648-79366992 (-)
PWK/PhJ MGP_PWKPhJ_G0021080
 protein coding gene Chr15:76635032-76685915 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020917
 protein coding gene Chr15:79118000-79166930 (-)
WSB/EiJ MGP_WSBEiJ_G0021390
 protein coding gene Chr15:79694769-79753979 (-)



Homology
more
  • Human Ortholog
    FAM227A, family with sequence similarity 227 member A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM227A, family with sequence similarity 227 member A
  • Links
    NCBI Gene ID: 646851
    UniProt: F5H4B4

  • Chr Location
    22q13.1; chr22:38578118-38656629 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Fam227a
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    59 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042564 Ensembl Gene Model | MGI Sequence Detail 46640 C57BL/6J ±  kb
transcript ENSMUST00000187519 Ensembl | MGI Sequence Detail 2283 Not Applicable  
polypeptide ENSMUSP00000139524 Ensembl | MGI Sequence Detail 625 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR029417 FAM227 Protein
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 42
    Diseases 1
    Phenotypes 26
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory