Ccdc192 Gene Detail

Summary

• Symbol
  Ccdc192
• Name
  coiled-coil domain containing 192
• Synonyms
  1700011I03Rik, 4930583I06Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1922694
  NCBI Gene: 75444
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr18:57666852-57864137 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 18, 32.15 cM, cytoband D2
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  1622 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922694	protein coding gene	Chr18:57666814-57864139 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024450	protein coding gene	Chr18:56971579-57185125 (+)
A/J	MGP_AJ_G0024416	protein coding gene	Chr18:54716795-54923374 (+)
AKR/J	MGP_AKRJ_G0024386	protein coding gene	Chr18:56229499-56452285 (+)
BALB/cJ	MGP_BALBcJ_G0024416	protein coding gene	Chr18:54886902-55083990 (+)
C3H/HeJ	MGP_C3HHeJ_G0024183	protein coding gene	Chr18:56420008-56621554 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024862	protein coding gene	Chr18:58785377-59012987 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022294	protein coding gene	Chr18:54311071-54509185 (+)
CAST/EiJ	MGP_CASTEiJ_G0023657	protein coding gene	Chr18:56458652-56662738 (+)
CBA/J	MGP_CBAJ_G0024153	protein coding gene	Chr18:60646178-60865348 (+)
DBA/2J	MGP_DBA2J_G0024283	protein coding gene	Chr18:54407385-54604317 (+)
FVB/NJ	MGP_FVBNJ_G0024250	protein coding gene	Chr18:53798493-53994229 (+)
LP/J	MGP_LPJ_G0024368	protein coding gene	Chr18:56932695-57138107 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024280	protein coding gene	Chr18:62247058-62456790 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024909	protein coding gene	Chr18:56337894-56544408 (+)
PWK/PhJ	MGP_PWKPhJ_G0023401	protein coding gene	Chr18:54437169-54636791 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023207	protein coding gene	Chr18:56418066-56635361 (+)
WSB/EiJ	MGP_WSBEiJ_G0023720	protein coding gene	Chr18:56257026-56461802 (+)

Homology

• Human Ortholog
  CCDC192, coiled-coil domain containing 192

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CCDC192, coiled-coil domain containing 192
  
• Synonyms
  LINC01183
• Links
  HGNC:49566

  NCBI Gene ID: 728586

  neXtProt AC: NX_P0DO97

  UniProt: P0DO97

  
  
• Chr Location
  5q23.2-q23.3; chr5:127702216-127941507 (+)  GRCh38

---

• Alliance of Genome Resources
  Ccdc192 stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: CCDC192
• Gene Tree
  Ccdc192
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  13 phenotype references
  

• All Mutations and Alleles
  6
• Endonuclease-mediated
  1
• Gene trapped
  1
• Radiation induced
  1
• Spontaneous
  1
• Targeted
  2
• Genomic Mutations
  2 involving Ccdc192
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  10 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  13

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Interactions

• Ccdc192 interacts with 39 markers (Mir23a, Mir23b, Mir92-2, ...) View All

Sequences &
Gene Models

• All Sequences
  51
• RefSeq
  14
• UniProt
  5
• CCDS
  CCDS50295.1, CCDS79645.1

• Ensembl
  ENSMUSG00000058925 (Evidence)
• NCBI Gene
  75444

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000058925	Ensembl Gene Model | MGI Sequence Detail	197286	C57BL/6J
transcript	ENSMUST00000123872	Ensembl | MGI Sequence Detail	829	Not Applicable
polypeptide	ENSMUSP00000114519	Ensembl | MGI Sequence Detail	254	Not Applicable

Protein
Information

• UniProt
  5 Sequences
• InterPro Domains
  IPR038817 Coiled-coil domain-containing protein 192

Molecular
Reagents

• All nucleic 13

  cDNA 13

  
  

  Microarray probesets 2

Other
Accession IDs

MGI:1925472

References

• Summaries
  All 29

  Diseases 1

  Phenotypes 13
• Earliest
  J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
• Latest
  J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67

TSS for Ccdc192:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr151205	Chr18:57666914-57666938 (+)	74 bp
Tssr5331	Chr18:57748641-57748643 (+)	81,790 bp
Tssr151206	Chr18:57791110-57791113 (+)	124,260 bp