About   Help   FAQ
Fam243 Gene Detail
Summary
  • Symbol
    Fam243
  • Name
    family with sequence similarity 243
  • Synonyms
    4930563D23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922578
    NCBI Gene: 75328
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:92115653-92118329 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 53.56 cM, cytoband C4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922578
 protein coding gene Chr16:92115651-92118329 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023055
 protein coding gene Chr16:93401065-93403743 (-)
A/J MGP_AJ_G0023023
 protein coding gene Chr16:89022545-89025223 (-)
AKR/J MGP_AKRJ_G0022993
 protein coding gene Chr16:91734214-91736892 (-)
BALB/cJ MGP_BALBcJ_G0023025
 protein coding gene Chr16:89551544-89554222 (-)
C3H/HeJ MGP_C3HHeJ_G0022786
 protein coding gene Chr16:92275630-92278308 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023472
 protein coding gene Chr16:96372188-96374866 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020974
 protein coding gene Chr16:86711271-86713952 (-)
CAST/EiJ MGP_CASTEiJ_G0022305
 protein coding gene Chr16:92870583-92873258 (-)
CBA/J MGP_CBAJ_G0022755
 protein coding gene Chr16:100522656-100525334 (-)
DBA/2J MGP_DBA2J_G0022889
 protein coding gene Chr16:88927439-88930117 (-)
FVB/NJ MGP_FVBNJ_G0022863
 protein coding gene Chr16:88053090-88055768 (-)
LP/J MGP_LPJ_G0022959
 protein coding gene Chr16:93090991-93093669 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022884
 protein coding gene Chr16:105026394-105029072 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023490
 protein coding gene Chr16:92242050-92244728 (-)
PWK/PhJ MGP_PWKPhJ_G0022050
 protein coding gene Chr16:89111519-89114193 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021880
 protein coding gene Chr16:91805493-91808140 (-)
WSB/EiJ MGP_WSBEiJ_G0022357
 protein coding gene Chr16:92484353-92487029 (-)



Homology
more
  • Human Ortholog
    C21orf140, chromosome 21 open reading frame 140
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C21orf140, chromosome 21 open reading frame 140
  • Synonyms
    FAM243A
  • Links
    NCBI Gene ID: 101928147
    neXtProt AC: NX_B9A014
    UniProt: B9A014

  • Chr Location
    chr21:34400112-34401072 (-)  GRCh38
Human Diseases
less
  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    71 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    1
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051728 Ensembl Gene Model | MGI Sequence Detail 2677 C57BL/6J ±  kb
transcript ENSMUST00000062638 Ensembl | MGI Sequence Detail 2677 Not Applicable  
polypeptide ENSMUSP00000049694 Ensembl | MGI Sequence Detail 251 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR037728 Uncharacterized protein C21orf140-like
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 90
    Developmental Gene Expression 1
    Diseases 4
    Phenotypes 71
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:335294 Redhead Y, et al., Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development. 2023 Apr 15;150(8):dev201077
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory