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Tmco5b Gene Detail
Summary
  • Symbol
    Tmco5b
  • Name
    transmembrane and coiled-coil domains 5B
  • Synonyms
    4930563P21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922525
    NCBI Gene: 75275
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:113116077-113127535 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 57.30 cM, cytoband E4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    390 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922525
 protein coding gene Chr2:113115440-113127535 (+)
129S1/SvImJ ENSMUSG00200007144
 protein coding gene Chr2:110003917-110015378 (+)
A/J ENSMUSG00195029091
 protein coding gene Chr2:110088730-110100172 (+)
AKR/J ENSMUSG00220004549
 protein coding gene Chr2:109964843-109976269 (+)
BALB/cJ ENSMUSG00180031212
 protein coding gene Chr2:109883962-109895406 (+)
C3H/HeJ ENSMUSG00175028623
 protein coding gene Chr2:110310595-110322193 (+)
C57BL/6NJ ENSMUSG00215020481
 protein coding gene Chr2:110017838-110029302 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024096
 protein coding gene Chr2:106223066-106234622 (+)
CAST/EiJ ENSTCUG00005005366
 protein coding gene Chr2:109260819-109272362 (+)
CBA/J ENSMUSG00210036961
 protein coding gene Chr2:110157956-110169398 (+)
DBA/2J ENSMUSG00185038068
 protein coding gene Chr2:109880374-109891811 (+)
FVB/NJ ENSMUSG00205018158
 protein coding gene Chr2:109102814-109114247 (+)
JF1/MsJ ENSUMUG00000002595
 protein coding gene Chr2:109702919-109714531 (+)
LP/J ENSMUSG00230005717
 protein coding gene Chr2:111666036-111677502 (+)
NOD/ShiLtJ ENSMUSG00190015081
 protein coding gene Chr2:110104746-110116176 (+)
NZO/HlLtJ ENSMUSG00225012570
 protein coding gene Chr2:119576579-119588027 (+)
PWK/PhJ ENSLUMG00010003110
 protein coding gene Chr2:109626913-109638492 (+)
SPRET/EiJ ENSMSPG00010030754
 protein coding gene Chr2:111897329-111908746 (+)
WSB/EiJ ENSIUOG00005030517
 protein coding gene Chr2:109796303-109808081 (+)



Homology
more
  • Human Ortholog
    TMCO5B, transmembrane and coiled-coil domains 5B (pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMCO5B, transmembrane and coiled-coil domains 5B (pseudogene)
  • Synonyms
    TMCO5BP
  • Links
    NCBI Gene ID: 100652857
    UniProt: A8MYB1

  • Chr Location
    chr15:33235750-33247555 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Tmco5b
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    10 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    4
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041255 Ensembl Gene Model | MGI Sequence Detail 11459 C57BL/6J ±  kb
transcript ENSMUST00000040856 Ensembl | MGI Sequence Detail 1237 Not Applicable  
polypeptide ENSMUSP00000042247 Ensembl | MGI Sequence Detail 307 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032597 transmembrane and coiled-coil domain-containing protein 5B
    (term hierarchy)
  • InterPro Domains
    IPR026617 Transmembrane and coiled-coil domain-containing protein 2/5
  • GlyGen
    Q80X59 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:123068 Pavel E, et al., Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region. Int J Dev Biol. 2007;51(4):273-81
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory