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Tmem269 Gene Detail
Summary
  • Symbol
    Tmem269
  • Name
    transmembrane protein 269
  • Synonyms
    4930538K18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922430
    NCBI Gene: 75180
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:119062252-119075414 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 55.34 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    499 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922430
 protein coding gene Chr4:119062209-119075754 (-)
129S1/SvImJ ENSMUSG00200012036
 protein coding gene Chr4:112966713-112979862 (-)
A/J ENSMUSG00195028857
 protein coding gene Chr4:114212435-114225969 (-)
AKR/J ENSMUSG00220019166
 protein coding gene Chr4:113573910-113587072 (-)
BALB/cJ ENSMUSG00180038218
 protein coding gene Chr4:112275541-112289068 (-)
C3H/HeJ ENSMUSG00175021806
 protein coding gene Chr4:113288734-113302261 (-)
C57BL/6NJ ENSMUSG00215029874
 protein coding gene Chr4:114400210-114413370 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026393
 protein coding gene Chr4:109759868-109772935 (-)
CAST/EiJ ENSTCUG00005043200
 protein coding gene Chr4:113096108-113109599 (-)
CBA/J ENSMUSG00210051941
 protein coding gene Chr4:112895231-112908757 (-)
DBA/2J ENSMUSG00185044219
 protein coding gene Chr4:114447438-114460970 (-)
FVB/NJ ENSMUSG00205019555
 protein coding gene Chr4:112371147-112384674 (-)
JF1/MsJ ENSUMUG00000007134
 protein coding gene Chr4:114354829-114368120 (-)
LP/J ENSMUSG00230041331
 protein coding gene Chr4:117784488-117797637 (-)
NOD/ShiLtJ ENSMUSG00190028865
 protein coding gene Chr4:112278199-112291373 (-)
NZO/HlLtJ ENSMUSG00225014790
 protein coding gene Chr4:123331126-123344294 (-)
PWK/PhJ ENSLUMG00010037414
 protein coding gene Chr4:111772918-111786204 (-)
SPRET/EiJ ENSMSPG00010032426
 protein coding gene Chr4:113855464-113868782 (-)
WSB/EiJ ENSIUOG00005036487
 protein coding gene Chr4:112587764-112600928 (-)



Homology
more
  • Human Ortholog
    TMEM269, transmembrane protein 269
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM269, transmembrane protein 269
  • Links
    NCBI Gene ID: 100129924
    UniProt: A0A1B0GVZ9

  • Chr Location
    1p34.2; chr1:42784991-42816619 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    3
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Tmem269
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028642 Ensembl Gene Model | MGI Sequence Detail 13163 C57BL/6J ±  kb
transcript ENSMUST00000212054 Ensembl | MGI Sequence Detail 1504 Not Applicable  
polypeptide ENSMUSP00000148286 Ensembl | MGI Sequence Detail 254 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:148802 Boles MK, et al., A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet. 2009;10:12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory