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Tex38 Gene Detail
Summary
  • Symbol
    Tex38
  • Name
    testis expressed 38
  • Synonyms
    4930544O15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922423
    NCBI Gene: 75173
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:115637031-115638215 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.06 cM, cytoband C7
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922423
 protein coding gene Chr4:115633178-115639925 (-)
129S1/SvImJ ENSMUSG00200046579
 protein coding gene Chr4:109532935-109534119 (-)
A/J ENSMUSG00195045023
 protein coding gene Chr4:110801003-110802187 (-)
AKR/J ENSMUSG00220011981
 protein coding gene Chr4:110145487-110146671 (-)
BALB/cJ ENSMUSG00180038501
 protein coding gene Chr4:108875307-108876491 (-)
C3H/HeJ ENSMUSG00175036343
 protein coding gene Chr4:109889751-109890935 (-)
C57BL/6NJ ENSMUSG00215022032
 protein coding gene Chr4:110960221-110961405 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026314
 protein coding gene Chr4:106220455-106221641 (-)
CAST/EiJ ENSTCUG00005019985
 protein coding gene Chr4:109658497-109659682 (-)
CBA/J ENSMUSG00210052988
 protein coding gene Chr4:109503265-109504449 (-)
DBA/2J ENSMUSG00185045945
 protein coding gene Chr4:111026787-111027971 (-)
FVB/NJ ENSMUSG00205027114
 protein coding gene Chr4:108972776-108973960 (-)
JF1/MsJ ENSUMUG00000033408
 protein coding gene Chr4:110924168-110925354 (-)
LP/J ENSMUSG00230042810
 protein coding gene Chr4:114350256-114351440 (-)
NOD/ShiLtJ ENSMUSG00190040852
 protein coding gene Chr4:108872691-108873875 (-)
NZO/HlLtJ ENSMUSG00225009682
 protein coding gene Chr4:119837638-119838822 (-)
PWK/PhJ ENSLUMG00010043900
 protein coding gene Chr4:108330706-108331890 (-)
SPRET/EiJ ENSMSPG00010023333
 protein coding gene Chr4:110403283-110404469 (-)
WSB/EiJ ENSIUOG00005042373
 protein coding gene Chr4:109186023-109187207 (-)



Homology
more
  • Human Ortholog
    TEX38, testis expressed 38
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEX38, testis expressed 38
  • Synonyms
    ATPAF1-AS1, C1orf223, THEG4
  • Links
    NCBI Gene ID: 374973
    UniProt: Q6PEX7

  • Chr Location
    1p33; chr1:46668855-46673594 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 3 alleles in 4 genetic backgrounds
    1 phenotype from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice exhibit male infertility with reduced sperm motility, malformed sperm heads and cytoplasmic droplets in spermatozoa that lack saccular elements and fail to migrate during epididymal maturation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    606
  • Tissues
    1
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000044556 Ensembl Gene Model | MGI Sequence Detail 1185 C57BL/6J ±  kb
    transcript ENSMUST00000106521 Ensembl | MGI Sequence Detail 802 Not Applicable  
    polypeptide ENSMUSP00000102131 Ensembl | MGI Sequence Detail 201 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 15
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:379207 Yang M, et al., Biogenesis and migration of the sperm cytoplasmic droplet require ARRDC5 and TEX38. Cell Rep. 2026 Jan 27;45(1):116731
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory