About   Help   FAQ
Tmem114 Gene Detail
Summary
  • Symbol
    Tmem114
  • Name
    transmembrane protein 114
  • Synonyms
    4930511J11Rik, Cldn26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921970
    NCBI Gene: 74720
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:8227140-8243000 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 3.84 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921970
 protein coding gene Chr16:8227139-8243000 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022491
 protein coding gene Chr16:5063552-5079216 (-)
A/J MGP_AJ_G0022453
 protein coding gene Chr16:4758142-4776716 (-)
AKR/J MGP_AKRJ_G0022430
 protein coding gene Chr16:5019323-5034999 (-)
BALB/cJ MGP_BALBcJ_G0022458
 protein coding gene Chr16:4923250-4946821 (-)
C3H/HeJ MGP_C3HHeJ_G0022225
 protein coding gene Chr16:5063490-5083441 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022907
 protein coding gene Chr16:5198927-5216548 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020428
 protein coding gene Chr16:4972132-4985002 (-)
CAST/EiJ MGP_CASTEiJ_G0021751
 protein coding gene Chr16:5083073-5117767 (-)
CBA/J MGP_CBAJ_G0022194
 protein coding gene Chr16:5402587-5425060 (-)
DBA/2J MGP_DBA2J_G0022325
 protein coding gene Chr16:4809483-4825087 (-)
FVB/NJ MGP_FVBNJ_G0022300
 protein coding gene Chr16:4797332-4814173 (-)
LP/J MGP_LPJ_G0022393
 protein coding gene Chr16:5042827-5064574 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022322
 protein coding gene Chr16:5194548-5213576 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022919
 protein coding gene Chr16:4985564-5001831 (-)
PWK/PhJ MGP_PWKPhJ_G0021491
 protein coding gene Chr16:4966199-5002020 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021322
 protein coding gene Chr16:5043893-5063846 (-)
WSB/EiJ MGP_WSBEiJ_G0021800
 protein coding gene Chr16:5027336-5046250 (-)



Homology
more
  • Human Ortholog
    TMEM114, transmembrane protein 114
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM114, transmembrane protein 114
  • Links
    NCBI Gene ID: 283953
    neXtProt AC: NX_B3SHH9
    UniProt: B3SHH9

  • Chr Location
    16p13.2; chr16:8526552-8590511 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    14
  • cDNA Data
    5
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74720 NCBI Gene Model | MGI Sequence Detail 15861 C57BL/6J ±  kb
    transcript NM_029070 RefSeq | MGI Sequence Detail 1406 C57BL/6  
    polypeptide Q9D563 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      Genomic 1
      cDNA 5
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:293870 Sun J, et al., CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction. Biol Reprod. 2020 Aug 4;103(2):183-194
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory