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Wbp2nl Gene Detail
Summary
  • Symbol
    Wbp2nl
  • Name
    WBP2 N-terminal like
  • Synonyms
    4930521I23Rik, PAWP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921966
    NCBI Gene: 74716
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:82183155-82198824 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 38.56 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    552 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921966
 protein coding gene Chr15:82183126-82198848 (+)
129S1/SvImJ ENSMUSG00200051759
 protein coding gene Chr15:79297490-79313168 (+)
A/J ENSMUSG00195042139
 protein coding gene Chr15:79229128-79244816 (+)
AKR/J ENSMUSG00220050151
 protein coding gene Chr15:79272286-79287983 (+)
BALB/cJ ENSMUSG00180051451
 protein coding gene Chr15:79106077-79121763 (+)
C3H/HeJ ENSMUSG00175046282
 protein coding gene Chr15:79417038-79432724 (+)
C57BL/6NJ ENSMUSG00215047963
 protein coding gene Chr15:79200723-79216402 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020079
 protein coding gene Chr15:76308115-76322538 (+)
CAST/EiJ ENSTCUG00005040020
 protein coding gene Chr15:78723120-78738565 (+)
CBA/J ENSMUSG00210047062
 protein coding gene Chr15:79192138-79207820 (+)
DBA/2J ENSMUSG00185044744
 protein coding gene Chr15:79215320-79231034 (+)
FVB/NJ ENSMUSG00205034334
 protein coding gene Chr15:78951912-78967655 (+)
JF1/MsJ ENSUMUG00000028426
 protein coding gene Chr15:78796916-78812371 (+)
LP/J ENSMUSG00230043000
 protein coding gene Chr15:82537871-82553551 (+)
NOD/ShiLtJ ENSMUSG00190051642
 protein coding gene Chr15:79209222-79224920 (+)
NZO/HlLtJ ENSMUSG00225048846
 protein coding gene Chr15:82876419-82892103 (+)
PWK/PhJ ENSLUMG00010051192
 protein coding gene Chr15:79007528-79023159 (+)
SPRET/EiJ ENSMSPG00010050123
 protein coding gene Chr15:80649340-80665047 (+)
WSB/EiJ ENSIUOG00005038752
 protein coding gene Chr15:79293421-79309130 (+)



Homology
more
  • Human Ortholog
    WBP2NL, WBP2 N-terminal like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WBP2NL, WBP2 N-terminal like
  • Synonyms
    GRAMD7, PAWP
  • Links
    NCBI Gene ID: 164684
    UniProt: Q6ICG8

  • Chr Location
    22q13.2; chr22:41998725-42058456 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    29 phenotype references
Male mice homozygous for a knock-out allele exhibit normal sperm morphology, acrosomal reaction, egg activation and fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022455 Ensembl Gene Model | MGI Sequence Detail 15670 C57BL/6J ±  kb
transcript ENSMUST00000023089 Ensembl | MGI Sequence Detail 1413 Not Applicable  
polypeptide ENSMUSP00000023089 Ensembl | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 54
    Diseases 1
    Gene Ontology 6
    Phenotypes 29
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory