About   Help   FAQ
Ifitm7 Gene Detail
Summary
  • Symbol
    Ifitm7
  • Name
    interferon induced transmembrane protein 7
  • Synonyms
    4933438K12Rik, Mil4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921732
    NCBI Gene: 74482
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:13799566-13804731 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 9.66 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    44 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921732
 protein coding gene Chr16:13799563-13804752 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022539
 protein coding gene Chr16:11004560-11009423 (-)
A/J MGP_AJ_G0022501
 protein coding gene Chr16:10388972-10394194 (-)
AKR/J MGP_AKRJ_G0022477
 protein coding gene Chr16:10843826-10850125 (-)
BALB/cJ MGP_BALBcJ_G0022505
 protein coding gene Chr16:10570555-10575710 (-)
C3H/HeJ MGP_C3HHeJ_G0022272
 protein coding gene Chr16:10937998-10943292 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022954
 protein coding gene Chr16:11153260-11158294 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020474
 protein coding gene Chr16:10471989-10473773 (-)
CAST/EiJ MGP_CASTEiJ_G0021799
 protein coding gene Chr16:10961229-10966687 (-)
CBA/J MGP_CBAJ_G0022241
 protein coding gene Chr16:11694228-11702012 (-)
DBA/2J MGP_DBA2J_G0022372
 protein coding gene Chr16:10382654-10388079 (-)
FVB/NJ MGP_FVBNJ_G0022348
 protein coding gene Chr16:10369553-10374578 (-)
LP/J MGP_LPJ_G0022440
 protein coding gene Chr16:10900404-10905399 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022370
 protein coding gene Chr16:11327295-11332282 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022967
 protein coding gene Chr16:10813578-10818587 (-)
PWK/PhJ MGP_PWKPhJ_G0021541
 protein coding gene Chr16:10650387-10652273 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021369
 protein coding gene Chr16:10810627-10812482 (-)
WSB/EiJ MGP_WSBEiJ_G0021847
 protein coding gene Chr16:10843653-10849693 (-)



Homology
more
  • Human Ortholog
    IFITM3, interferon induced transmembrane protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFITM3, interferon induced transmembrane protein 3
  • Synonyms
    1-8U, DSPA2b, IP15
  • Links
    NCBI Gene ID: 10410
    neXtProt AC: NX_Q01628
    UniProt: Q01628

  • Chr Location
    11p15.5; chr11:319676-329475 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human IFITM3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
DNA-templated transcription
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    806
  • Tissues
    17
  • cDNA Data
    6
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
    33
  • RefSeq
    2
  • UniProt
    3
Representative SequencesLengthStrain/SpeciesFlank
genomic 74482 NCBI Gene Model | MGI Sequence Detail 5166 C57BL/6J ±  kb
transcript NM_001270718 RefSeq | MGI Sequence Detail 865 C57BL/6  
polypeptide NP_001257647 RefSeq | MGI Sequence Detail 113 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR007593 CD225/Dispanin family
Molecular
Reagents
less
  • All nucleic 9
    cDNA 6
    Primer pair 2
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/21/2023
MGI 6.22 		The Jackson Laboratory