About   Help   FAQ
Klrg2 Gene Detail
Summary
  • Symbol
    Klrg2
  • Name
    killer cell lectin-like receptor subfamily G, member 2
  • Synonyms
    2310020F24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921503
    NCBI Gene: 74253
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:38602628-38614177 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 17.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    391 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921503
 protein coding gene Chr6:38593264-38615750 (-)
129S1/SvImJ ENSMUSG00200044474
 protein coding gene Chr6:35657954-35669502 (-)
A/J ENSMUSG00195036107
 protein coding gene Chr6:35629644-35641192 (-)
AKR/J ENSMUSG00220008362
 protein coding gene Chr6:35228296-35239844 (-)
BALB/cJ ENSMUSG00180045538
 protein coding gene Chr6:35758092-35769640 (-)
C3H/HeJ ENSMUSG00175048092
 protein coding gene Chr6:35585095-35596667 (-)
C57BL/6NJ ENSMUSG00215041807
 protein coding gene Chr6:35664453-35676003 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028238
 protein coding gene Chr6:33250556-33262600 (-)
CAST/EiJ ENSTCUG00005035260
 protein coding gene Chr6:35159336-35170932 (-)
CBA/J ENSMUSG00210051932
 protein coding gene Chr6:35636988-35648560 (-)
DBA/2J ENSMUSG00185041473
 protein coding gene Chr6:35737581-35749152 (-)
FVB/NJ ENSMUSG00205047707
 protein coding gene Chr6:35713924-35725492 (-)
JF1/MsJ ENSUMUG00000015897
 protein coding gene Chr6:35386076-35398078 (-)
LP/J ENSMUSG00230042224
 protein coding gene Chr6:36663480-36675028 (-)
NOD/ShiLtJ ENSMUSG00190032614
 protein coding gene Chr6:35503998-35515546 (-)
NZO/HlLtJ ENSMUSG00225007993
 protein coding gene Chr6:38646080-38657629 (-)
PWK/PhJ ENSLUMG00010042839
 protein coding gene Chr6:35160088-35172062 (-)
SPRET/EiJ ENSMSPG00010023605
 protein coding gene Chr6:35771495-35782700 (-)
WSB/EiJ ENSIUOG00005029247
 protein coding gene Chr6:35840445-35852008 (-)



Homology
more
  • Human Ortholog
    KLRG2, killer cell lectin like receptor G2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLRG2, killer cell lectin like receptor G2
  • Synonyms
    CLEC15B
  • Links
    NCBI Gene ID: 346689
    UniProt: A4D1S0

  • Chr Location
    7q34; chr7:139427098-139483674 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000071537 Ensembl Gene Model | MGI Sequence Detail 11550 C57BL/6J ±  kb
    transcript ENSMUST00000096030 Ensembl | MGI Sequence Detail 2276 Not Applicable  
    polypeptide ENSMUSP00000093732 Ensembl | MGI Sequence Detail 387 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000029581 killer cell lectin-like receptor subfamily G member 2
      (term hierarchy)
    • InterPro Domains
      IPR016187 C-type lectin fold
      IPR001304 C-type lectin-like
      IPR016186 C-type lectin-like/link domain superfamily
      IPR043318 Killer cell lectin-like receptor subfamily G member 2
      IPR033992 Natural killer cell receptor-like, C-type lectin-like domain
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 2
    References
    more
    • Summaries
      All 25
      Gene Ontology 1
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory