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Phactr3 Gene Detail
Summary
  • Symbol
    Phactr3
  • Name
    phosphatase and actin regulator 3
  • Synonyms
    1500003N10Rik, 4930415A02Rik, scapinin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921439
    NCBI Gene: 74189
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:177760768-177980285 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 99.67 cM, cytoband H4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6671 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921439
 protein coding gene Chr2:177760768-177980285 (+)
129S1/SvImJ ENSMUSG00200001897
 protein coding gene Chr2:173785313-174004845 (+)
A/J ENSMUSG00195001034
 protein coding gene Chr2:174019816-174239388 (+)
AKR/J ENSMUSG00220033980
 protein coding gene Chr2:171698767-171918321 (+)
BALB/cJ ENSMUSG00180000321
 protein coding gene Chr2:171821264-172040808 (+)
C3H/HeJ ENSMUSG00175004174
 protein coding gene Chr2:172985457-173205012 (+)
C57BL/6NJ ENSMUSG00215025175
 protein coding gene Chr2:171920224-172139771 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024765
 protein coding gene Chr2:167618208-167842680 (+)
CAST/EiJ ENSTCUG00005008216
 protein coding gene Chr2:171269599-171493097 (+)
CBA/J ENSMUSG00210039172
 protein coding gene Chr2:172299411-172518945 (+)
DBA/2J ENSMUSG00185020507
 protein coding gene Chr2:173544850-173764406 (+)
FVB/NJ ENSMUSG00205002360
 protein coding gene Chr2:172345284-172564986 (+)
JF1/MsJ ENSUMUG00000033368
 protein coding gene Chr2:174705484-174927998 (+)
LP/J ENSMUSG00230020235
 protein coding gene Chr2:175436424-175655958 (+)
NOD/ShiLtJ ENSMUSG00190033005
 protein coding gene Chr2:171839846-172059376 (+)
NZO/HlLtJ ENSMUSG00225006210
 protein coding gene Chr2:183524320-183743857 (+)
PWK/PhJ ENSLUMG00010037706
 protein coding gene Chr2:172131269-172353076 (+)
SPRET/EiJ ENSMSPG00010003577
 protein coding gene Chr2:174609808-174828053 (+)
WSB/EiJ ENSIUOG00005021846
 protein coding gene Chr2:171880350-172099892 (+)



Homology
more
  • Human Ortholog
    PHACTR3, phosphatase and actin regulator 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHACTR3, phosphatase and actin regulator 3
  • Synonyms
    C20orf101, H17739, PPP1R123, SCAPIN1, SCAPININ
  • Links
    NCBI Gene ID: 116154
    UniProt: Q96KR7

  • Chr Location
    20q13.32-q13.33; chr20:59577495-59847711 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    650
  • Tissues
    44
  • cDNA Data
    13
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74189 NCBI Gene Model | MGI Sequence Detail 219518 C57BL/6J ±  kb
transcript NM_028806 RefSeq | MGI Sequence Detail 5076 C57BL/6  
polypeptide Q8BYK5 UniProt | EBI | MGI Sequence Detail 558 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 13
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1921108
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory