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Tm9sf1 Gene Detail
Summary
  • Symbol
    Tm9sf1
  • Name
    transmembrane 9 superfamily member 1
  • Synonyms
    1200014D02Rik, MP70
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921390
    NCBI Gene: 74140
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55873422-55881263 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    215 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921390
 protein coding gene Chr14:55873422-55881263 (-)
129S1/SvImJ ENSMUSG00200041997
 protein coding gene Chr14:44461125-44468966 (-)
A/J ENSMUSG00195030777
 protein coding gene Chr14:44677848-44685689 (-)
AKR/J ENSMUSG00220025386
 protein coding gene Chr14:44005749-44013590 (-)
BALB/cJ ENSMUSG00180048177
 protein coding gene Chr14:44301565-44309406 (-)
C3H/HeJ ENSMUSG00175038261
 protein coding gene Chr14:45983909-45991750 (-)
C57BL/6NJ ENSMUSG00215046538
 protein coding gene Chr14:44196634-44204475 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019306
 protein coding gene Chr14:47059083-47068013 (-)
CAST/EiJ ENSTCUG00005044315
 protein coding gene Chr14:45979033-45986878 (-)
CBA/J ENSMUSG00210039121
 protein coding gene Chr14:44664445-44672286 (-)
DBA/2J ENSMUSG00185053735
 protein coding gene Chr14:49731694-49739534 (-)
FVB/NJ ENSMUSG00205033301
 protein coding gene Chr14:44074992-44082832 (-)
JF1/MsJ ENSUMUG00000028436
 protein coding gene Chr14:60963642-60971477 (-)
LP/J ENSMUSG00230051594
 protein coding gene Chr14:61826993-61834834 (-)
NOD/ShiLtJ ENSMUSG00190043575
 protein coding gene Chr14:44438384-44446224 (-)
NZO/HlLtJ ENSMUSG00225044863
 protein coding gene Chr14:52117359-52125200 (-)
PWK/PhJ ENSLUMG00010042841
 protein coding gene Chr14:43887099-43894940 (-)
SPRET/EiJ ENSMSPG00010045146
 protein coding gene Chr14:47291140-47299049 (-)
WSB/EiJ ENSIUOG00005038877
 protein coding gene Chr14:43879079-43886920 (-)



Homology
more
  • Human Ortholog
    TM9SF1, transmembrane 9 superfamily member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TM9SF1, transmembrane 9 superfamily member 1
  • Synonyms
    HMP70, MP70
  • Links
    NCBI Gene ID: 10548
    UniProt: O15321

  • Chr Location
    14q12; chr14:24189140-24196287 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    630
  • Tissues
    17
  • cDNA Data
    79
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74140 NCBI Gene Model | MGI Sequence Detail 7842 C57BL/6J ±  kb
    transcript NM_001360063 RefSeq | MGI Sequence Detail 2525 C57BL/6  
    polypeptide Q9DBU0 UniProt | EBI | MGI Sequence Detail 606 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 79
      cDNA 79
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2145706
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:373093 Wang H, et al., TM9SF1 inhibits colorectal cancer metastasis by targeting Vimentin for Tollip-mediated selective autophagic degradation. Cell Death Differ. 2025 Oct;32(10):1871-1885
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory