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Rin2 Gene Detail
Summary
  • Symbol
    Rin2
  • Name
    Ras and Rab interactor 2
  • Synonyms
    2010003K16Rik, 4632403N06Rik, RASSF4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921280
    NCBI Gene: 74030
  • Alliance
    genome feature page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:145613647-145729536 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 71.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3070 from dbSNP Build 142
  • Strain Annotations
    24
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921280
 protein coding gene Chr2:145517135-145729536 (+)
129S1/SvImJ ENSMUSGG00200054595
 protein coding gene Chr2:142776967-142842100 (+)
A/J ENSMUSG00195019329
 protein coding gene Chr2:142866442-142903049 (+)
A/J ENSMUSGG00195055144
 protein coding gene Chr2:142902898-142968191 (+)
AKR/J ENSMUSGG00220054903
 protein coding gene Chr2:142486558-142551692 (+)
BALB/cJ ENSMUSGG00180055441
 protein coding gene Chr2:142564740-142630019 (+)
BALB/cJ ENSMUSG00180039084
 protein coding gene Chr2:142528285-142564891 (+)
C3H/HeJ ENSMUSG00175038590
 protein coding gene Chr2:143075334-143111934 (+)
C3H/HeJ ENSMUSGG00175054758
 protein coding gene Chr2:143111783-143177059 (+)
C57BL/6NJ ENSMUSG00215026714
 protein coding gene Chr2:142590014-142691681 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024392
 protein coding gene Chr2:137992066-138107379 (+)
CAST/EiJ ENSTCUGG00005053878
 protein coding gene Chr2:141763204-141831154 (+)
CBA/J ENSMUSGG00210054759
 protein coding gene Chr2:143031002-143096280 (+)
CBA/J ENSMUSG00210037754
 protein coding gene Chr2:142994547-143031153 (+)
DBA/2J ENSMUSGG00185057368
 protein coding gene Chr2:142655524-142720648 (+)
FVB/NJ ENSMUSGG00205054044
 protein coding gene Chr2:141839500-141904605 (+)
JF1/MsJ ENSUMUGG00000058427
 protein coding gene Chr2:142444981-142510119 (+)
LP/J ENSMUSGG00230055455
 protein coding gene Chr2:144359585-144424684 (+)
NOD/ShiLtJ ENSMUSGG00190054560
 protein coding gene Chr2:142699253-142764545 (+)
NOD/ShiLtJ ENSMUSG00190038973
 protein coding gene Chr2:142662802-142699404 (+)
NZO/HlLtJ ENSMUSGG00225055311
 protein coding gene Chr2:152347869-152412990 (+)
PWK/PhJ ENSLUMGG00010053795
 protein coding gene Chr2:142473946-142539219 (+)
SPRET/EiJ ENSMSPG00010023665
 protein coding gene Chr2:144917249-145028873 (+)
WSB/EiJ ENSIUOGG00005053874
 protein coding gene Chr2:142474536-142539779 (+)



Homology
more
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
  • Synonyms
    MACS, RASSF4
  • Links
    NCBI Gene ID: 54453
    UniProt: Q8WYP3

  • Chr Location
    20p11.23; chr20:19757599-20003571 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    112
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74030 NCBI Gene Model | MGI Sequence Detail 115890 C57BL/6J ±  kb
transcript NM_001406510 RefSeq | MGI Sequence Detail 4736 C57BL/6  
polypeptide Q9D684 UniProt | EBI | MGI Sequence Detail 903 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 112
    cDNA 112

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917119, MGI:2139415
References
more
  • Summaries
    All 38
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory