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Rlig1 Gene Detail
Summary
  • Symbol
    Rlig1
  • Name
    RNA 5'-phosphate and 3'-OH ligase 1
  • Synonyms
    4930430F08Rik, 4930571E09Rik, A730088G13Rik, C430008C19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921197
    NCBI Gene: 68281
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:100408136-100425252 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 51.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921197
protein coding gene Chr10:100408127-100426285 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017692
protein coding gene Chr10:102441750-102454704 (-)
A/J MGP_AJ_G0017671
protein coding gene Chr10:98722061-98739100 (-)
AKR/J MGP_AKRJ_G0017633
protein coding gene Chr10:101547987-101560071 (-)
BALB/cJ MGP_BALBcJ_G0017635
protein coding gene Chr10:99028171-99041302 (-)
C3H/HeJ MGP_C3HHeJ_G0017460
protein coding gene Chr10:101574424-101587961 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018092
protein coding gene Chr10:106016598-106038097 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015771
protein coding gene Chr10:94105053-94117204 (-)
CAST/EiJ MGP_CASTEiJ_G0017021
protein coding gene Chr10:101622295-101635612 (-)
CBA/J MGP_CBAJ_G0017429
protein coding gene Chr10:110087749-110099872 (-)
DBA/2J MGP_DBA2J_G0017534
protein coding gene Chr10:97809186-97821601 (-)
FVB/NJ MGP_FVBNJ_G0017528
protein coding gene Chr10:97007160-97019502 (-)
LP/J MGP_LPJ_G0017608
protein coding gene Chr10:103055932-103069566 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017558
protein coding gene Chr10:111386577-111401607 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018130
protein coding gene Chr10:101522250-101537870 (-)
PWK/PhJ MGP_PWKPhJ_G0016803
protein coding gene Chr10:97881279-97893586 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016593
protein coding gene Chr10:100296826-100309945 (-)
WSB/EiJ MGP_WSBEiJ_G0017081
protein coding gene Chr10:101506522-101518648 (-)



Homology
more
  • Human Ortholog
    RLIG1, RNA 5'-phosphate and 3'-OH ligase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RLIG1, RNA 5'-phosphate and 3'-OH ligase 1
  • Synonyms
    C12orf29, Rnl
  • Links
    NCBI Gene ID: 91298
    neXtProt AC: NX_Q8N999
    UniProt: Q8N999

  • Chr Location
    12q21.32; chr12:88033846-88050160 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68281 NCBI Gene Model | MGI Sequence Detail 17117 C57BL/6J ±  kb
transcript NM_175128 RefSeq | MGI Sequence Detail 2419 C57BL/6  
polypeptide Q8BHN7 UniProt | EBI | MGI Sequence Detail 327 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 16

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915531, MGI:1923190, MGI:2143861, MGI:2442571
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory