Prr27 MGI Mouse Gene Detail - MGI:1921029

Symbol

Prr27
Name

proline rich 27
Synonyms

4930432K09Rik

Feature Type

protein coding gene
IDs

MGI:1921029
NCBI Gene: 73779
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr5:87973556-87994245 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 43.56 cM, cytoband E2
Mapping Data

3 experiments

SNPs within 2kb

711 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921029	protein coding gene	Chr5:87973545-87994246 (+)
129S1/SvImJ	ENSMUSG00200009216	protein coding gene	Chr5:83704883-83725579 (+)
A/J	ENSMUSG00195023986	protein coding gene	Chr5:82875112-82895815 (+)
AKR/J	ENSMUSG00220011257	protein coding gene	Chr5:83015203-83035905 (+)
BALB/cJ	ENSMUSG00180022851	protein coding gene	Chr5:82707906-82728605 (+)
C3H/HeJ	ENSMUSG00175038418	protein coding gene	Chr5:84783065-84803771 (+)
C57BL/6NJ	ENSMUSG00215019575	protein coding gene	Chr5:83568153-83588853 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027362	protein coding gene	Chr5:80784351-80802308 (+)
CAST/EiJ	ENSTCUG00005036737	protein coding gene	Chr5:82414282-82434589 (+)
CBA/J	ENSMUSG00210005542	protein coding gene	Chr5:83598362-83619063 (+)
DBA/2J	ENSMUSG00185038156	protein coding gene	Chr5:85517559-85538268 (+)
FVB/NJ	ENSMUSG00205022076	protein coding gene	Chr5:82421663-82442380 (+)
JF1/MsJ	ENSUMUG00000000877	protein coding gene	Chr5:89974775-89993985 (+)
LP/J	ENSMUSG00230001453	protein coding gene	Chr5:90234885-90255580 (+)
NOD/ShiLtJ	ENSMUSG00190037445	protein coding gene	Chr5:82459642-82480346 (+)
NZO/HlLtJ	ENSMUSG00225007777	protein coding gene	Chr5:95263859-95284566 (+)
PWK/PhJ	ENSLUMG00010025515	protein coding gene	Chr5:82482915-82503837 (+)
SPRET/EiJ	ENSMSPG00010030439	protein coding gene	Chr5:84768957-84789133 (+)
WSB/EiJ	ENSIUOG00005028556	protein coding gene	Chr5:85417160-85437931 (+)

Human Ortholog

PRR27, proline rich 27

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PRR27, proline rich 27
Synonyms

C4orf40
Links

HGNC:33193

NCBI Gene ID: 401137

UniProt: Q6MZM9
Chr Location

4q13.3; chr4:70133616-70176799 (+) GRCh38

MGI Vertebrate Homology

Prr27 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: PRR27
Gene Tree

Prr27

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Chemically induced (other)

2
Endonuclease-mediated

1
Radiation induced

1
Spontaneous

1
Targeted

3
Genomic Mutations

4 involving Prr27
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

37 strains or lines available

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

646
Tissues

7
cDNA Data

6
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

39
RefSeq

5
UniProt

4
CCDS

CCDS39134.1, CCDS51535.1

Ensembl

ENSMUSG00000002240 (Evidence)
NCBI Gene

73779

			Length	Strain/Species	Flank
genomic	73779	NCBI Gene Model \| MGI Sequence Detail	20690	C57BL/6J	± kb
transcript	NM_001163551	RefSeq \| MGI Sequence Detail	1325	ZRU/MplStud
polypeptide	NP_001157023	RefSeq \| MGI Sequence Detail	352	ZRU/MplStud

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UniProt

4 Sequences
InterPro Domains

IPR033533 Proline-rich protein 27

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All nucleic 8

Genomic 2

cDNA 6

Microarray probesets 2

Summaries

All 33

Developmental Gene Expression 2

Phenotypes 13
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Prr27:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr46931	Chr5:87973534-87973613 (+)	18 bp
Tssr46932	Chr5:87973618-87973630 (+)	68 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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