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Capstert Gene Detail
Summary
  • Symbol
    Capstert
  • Name
    catsper channel auxiliary subunit tau
  • Synonyms
    1700052H20Rik, 4930408G06Rik, Als2cr11, Als2cr11b, C2cd6, C2cd6b, Gm33589
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920713
    NCBI Gene: 73463
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:59036275-59134059 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 29.20 cM, cytoband C2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2056 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920713
 protein coding gene Chr1:59036275-59134283 (-)
129S1/SvImJ ENSMUSG00200018484
 protein coding gene Chr1:56535237-56634403 (-)
A/J ENSMUSG00195026678
 protein coding gene Chr1:56073166-56172147 (-)
AKR/J ENSMUSG00220039010
 protein coding gene Chr1:56163355-56262338 (-)
BALB/cJ ENSMUSG00180014054
 protein coding gene Chr1:56314472-56413911 (-)
C3H/HeJ ENSMUSG00175000960
 protein coding gene Chr1:56450639-56549602 (-)
C57BL/6NJ ENSMUSG00215027532
 protein coding gene Chr1:56382445-56481451 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014173
 protein coding gene Chr1:52770822-52815690 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210031657
 protein coding gene Chr1:56135496-56234733 (-)
DBA/2J ENSMUSG00185054600
 protein coding gene Chr1:57255198-57354450 (-)
FVB/NJ ENSMUSG00205021539
 protein coding gene Chr1:56096479-56195454 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230024766
 protein coding gene Chr1:57255772-57354934 (-)
NOD/ShiLtJ ENSMUSG00190033703
 protein coding gene Chr1:56295563-56394999 (-)
NZO/HlLtJ ENSMUSG00225007564
 protein coding gene Chr1:60462789-60561798 (-)
PWK/PhJ ENSLUMG00010023920
 protein coding gene Chr1:55735868-55835079 (-)
SPRET/EiJ ENSMSPG00010022834
 protein coding gene Chr1:57680075-57779117 (-)
WSB/EiJ ENSIUOG00005020221
 protein coding gene Chr1:55920598-56019717 (-)



Homology
more
  • Human Ortholog
    CATSPERT, catsper channel auxiliary subunit tau
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CATSPERT, catsper channel auxiliary subunit tau
  • Synonyms
    ALS2CR11, C2CD6, SPGF68
  • Links
    NCBI Gene ID: 151254
    UniProt: Q53TS8

  • Chr Location
    2q33.1; chr2:201487421-201619178 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CATSPERT associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility associated with decreased hyperactivate sperm motility and reduced Cat Sper calcium channel capacity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000072295 Ensembl Gene Model | MGI Sequence Detail 97785 C57BL/6J ±  kb
    transcript ENSMUST00000238949 Ensembl | MGI Sequence Detail 7029 Not Applicable  
    polypeptide ENSMUSP00000159118 Ensembl | MGI Sequence Detail 2282 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • InterPro Domains
      IPR031462 Cation channel sperm-associated targeting subunit tau
      IPR048363 Cation channel sperm-associated targeting subunit tau, C2 domain
    • GlyGen
      A0A5F8MPU3 1 site
    Molecular
    Reagents
    less
    • All nucleic 13
      Genomic 3
      cDNA 10

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1915429, MGI:5592748, MGI:5898370, MGI:5898371, MGI:8328272
    References
    more
    • Summaries
      All 33
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:321418 Hwang JY, et al., C2cd6-encoded CatSpertau targets sperm calcium channel to Ca(2+) signaling domains in the flagellar membrane. Cell Rep. 2022 Jan 18;38(3):110226
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory