Msl3l2 MGI Mouse Gene Detail - MGI:1920640

Symbol

Msl3l2
Name

MSL3 like 2
Synonyms

1700060H10Rik

Feature Type

protein coding gene
IDs

MGI:1920640
NCBI Gene: 73390
Alliance

genome feature page
Transcription Start Sites

5 TSS

Sequence Map

Chr10:55983013-55992976 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 28.50 cM
Mapping Data

1 experiment

SNPs within 2kb

422 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920640	protein coding gene	Chr10:55959931-55992976 (+)
129S1/SvImJ	ENSMUSG00200025099	protein coding gene	Chr10:52896217-52906180 (+)
A/J	ENSMUSG00195026936	protein coding gene	Chr10:53149588-53159552 (+)
AKR/J	ENSMUSG00220035951	protein coding gene	Chr10:52856303-52866267 (+)
BALB/cJ	ENSMUSG00180021892	protein coding gene	Chr10:53279025-53288989 (+)
C3H/HeJ	ENSMUSG00175023914	protein coding gene	Chr10:53114036-53123999 (+)
C57BL/6NJ	ENSMUSG00215014810	protein coding gene	Chr10:52801537-52811500 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015325	protein coding gene	Chr10:50757363-50767455 (+)
CAST/EiJ	ENSTCUG00005028185	protein coding gene	Chr10:52971937-52981955 (+)
CBA/J	ENSMUSG00210031415	protein coding gene	Chr10:52927543-52937506 (+)
DBA/2J	ENSMUSG00185040451	protein coding gene	Chr10:53079426-53089389 (+)
FVB/NJ	ENSMUSG00205024862	protein coding gene	Chr10:52992007-53001970 (+)
JF1/MsJ	ENSUMUG00000018937	protein coding gene	Chr10:52707864-52717859 (+)
LP/J	ENSMUSG00230023047	protein coding gene	Chr10:54880689-54890652 (+)
NOD/ShiLtJ	ENSMUSG00190032060	protein coding gene	Chr10:53261764-53271729 (+)
NZO/HlLtJ	ENSMUSG00225022302	protein coding gene	Chr10:59161594-59171557 (+)
PWK/PhJ	ENSLUMG00010023143	protein coding gene	Chr10:52925356-52935361 (+)
SPRET/EiJ	ENSMSPG00010024481	protein coding gene	Chr10:54466778-54469356 (+)
WSB/EiJ	ENSIUOG00005037709	protein coding gene	Chr10:52913813-52923799 (+)

Human Ortholog

MSL3, MSL complex subunit 3

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MSL3, MSL complex subunit 3
Synonyms

MRSXBA, MRXS36, MRXSBA, MSL3L1
Links

HGNC:7370

NCBI Gene ID: 10943

UniProt: Q8N5Y2
Chr Location

Xp22.2; chrX:11758159-11775772 (+) GRCh38

Human Ortholog

MSL3B, MSL complex subunit 3B
Synonyms

MSL3L2, MSL3P1
Links

HGNC:17837

NCBI Gene ID: 151507

UniProt: P0C860
Chr Location

2q37.1; chr2:233864663-233868386 (-) GRCh38

MGI Vertebrate Homology

Msl3l2 stringent orthology
2 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: MSL3, MSL3B
Gene Tree

Msl3l2

Diseases

1 with human MSL3 associations

				Human Disease	Mouse Models
				Basilicata-Akhtar syndrome IDs Basilicata-Akhtar syndrome DOID:0111838 OMIM:301032

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

4
Chemically induced (other)

1
Endonuclease-mediated

2
Radiation induced

1
Genomic Mutations

2 involving Msl3l2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

14 strains or lines available

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All GO Annotations

13
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

20

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

35
RefSeq

4
UniProt

1
CCDS

CCDS48561.1

Ensembl

ENSMUSG00000047669 (Evidence)
NCBI Gene

73390

			Length	Strain/Species	Flank
genomic	ENSMUSG00000047669	Ensembl Gene Model \| MGI Sequence Detail	9964	C57BL/6J	± kb
transcript	ENSMUST00000063138	Ensembl \| MGI Sequence Detail	2140	Not Applicable
polypeptide	ENSMUSP00000051220	Ensembl \| MGI Sequence Detail	371	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR008676 MRG

IPR038217 MRG, C-terminal domain superfamily

IPR026541 MRG domain

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All nucleic 20

cDNA 20

Microarray probesets 1

Summaries

All 27

Gene Ontology 4

Phenotypes 7
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Msl3l2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr93353	Chr10:55982979-55983033 (+)	-7 bp
Tssr93354	Chr10:55983041-55983055 (+)	35 bp
Tssr93355	Chr10:55991046-55991057 (+)	8,039 bp
Tssr93356	Chr10:55991418-55991480 (+)	8,436 bp
Tssr93357	Chr10:55991488-55991519 (+)	8,491 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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