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Prss52 Gene Detail
Summary
  • Symbol
    Prss52
  • Name
    serine protease 52
  • Synonyms
    1700049K14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920632
    NCBI Gene: 73382
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:64341772-64351200 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 33.35 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    125 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920632
protein coding gene Chr14:64341735-64351204 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021471
protein coding gene Chr14:58668776-58678234 (+)
A/J MGP_AJ_G0021430
protein coding gene Chr14:57319653-57329035 (+)
AKR/J MGP_AKRJ_G0021406
protein coding gene Chr14:59347400-59356768 (+)
BALB/cJ MGP_BALBcJ_G0021436
protein coding gene Chr14:57276097-57285471 (+)
C3H/HeJ MGP_C3HHeJ_G0021213
protein coding gene Chr14:58976480-58985945 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021875
protein coding gene Chr14:61407519-61416977 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019415
protein coding gene Chr14:55253398-55262502 (+)
CAST/EiJ MGP_CASTEiJ_G0020730
protein coding gene Chr14:55430935-55440125 (+)
CBA/J MGP_CBAJ_G0021180
protein coding gene Chr14:63267660-63277048 (+)
DBA/2J MGP_DBA2J_G0021303
protein coding gene Chr14:56993633-57003102 (+)
FVB/NJ MGP_FVBNJ_G0021282
protein coding gene Chr14:56382229-56391993 (+)
LP/J MGP_LPJ_G0021378
protein coding gene Chr14:59702441-59712904 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021311
protein coding gene Chr14:62448997-62458402 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021898
protein coding gene Chr14:58508645-58518014 (+)
PWK/PhJ MGP_PWKPhJ_G0020474
protein coding gene Chr14:53669471-53678751 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020307
protein coding gene Chr14:54470675-54479861 (+)
WSB/EiJ MGP_WSBEiJ_G0020783
protein coding gene Chr14:58823511-58832886 (+)



Homology
more
  • Human Ortholog
    PRSS52P, serine protease 52, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS52P, serine protease 52, pseudogene
  • Links
    NCBI Gene ID: 100419209

  • Chr Location
    chr8:10474789-10475045 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73382 NCBI Gene Model | MGI Sequence Detail 9429 C57BL/6J ±  kb
transcript NM_028525 RefSeq | MGI Sequence Detail 1054 Not Specified  
polypeptide Q9D9M0 UniProt | EBI | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory