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Rassf6 Gene Detail
Summary
  • Symbol
    Rassf6
  • Name
    Ras association (RalGDS/AF-6) domain family member 6
  • Synonyms
    1600016B17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920496
    NCBI Gene: 73246
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:90750935-90788516 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 44.78 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1407 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920496
 protein coding gene Chr5:90750933-90788594 (-)
129S1/SvImJ ENSMUSG00200007299
 protein coding gene Chr5:86478157-86506723 (-)
A/J ENSMUSG00195024626
 protein coding gene Chr5:85653703-85682235 (-)
AKR/J ENSMUSG00220010930
 protein coding gene Chr5:85799405-85827933 (-)
BALB/cJ ENSMUSG00180021231
 protein coding gene Chr5:85504715-85533275 (-)
C3H/HeJ ENSMUSG00175040796
 protein coding gene Chr5:87600354-87628915 (-)
C57BL/6NJ ENSMUSG00215018867
 protein coding gene Chr5:86346679-86375206 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027391
 protein coding gene Chr5:83773806-83811471 (-)
CAST/EiJ ENSTCUG00005036861
 protein coding gene Chr5:85257280-85286086 (-)
CBA/J ENSMUSG00210005283
 protein coding gene Chr5:86400144-86428697 (-)
DBA/2J ENSMUSG00185038791
 protein coding gene Chr5:88321080-88349640 (-)
FVB/NJ ENSMUSG00205027001
 protein coding gene Chr5:85200756-85229317 (-)
JF1/MsJ ENSUMUG00000036771
 protein coding gene Chr5:92604894-92634408 (-)
LP/J ENSMUSG00230023933
 protein coding gene Chr5:93004508-93033080 (-)
NOD/ShiLtJ ENSMUSG00190025793
 protein coding gene Chr5:85282629-85311186 (-)
NZO/HlLtJ ENSMUSG00225007966
 protein coding gene Chr5:98152037-98180601 (-)
PWK/PhJ ENSLUMG00010026591
 protein coding gene Chr5:85271408-85300349 (-)
SPRET/EiJ ENSMSPG00010029584
 protein coding gene Chr5:87675520-87713110 (-)
WSB/EiJ ENSIUOG00005026668
 protein coding gene Chr5:88284193-88312810 (-)



Homology
more
  • Human Ortholog
    RASSF6, Ras association domain family member 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASSF6, Ras association domain family member 6
  • Links
    NCBI Gene ID: 166824
    UniProt: Q6ZTQ3

  • Chr Location
    4q13.3; chr4:73571550-73620631 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    4
  • Radiation induced
    1
  • Spontaneous
    1
  • Genomic Mutations
    4 involving Rassf6
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    673
  • Tissues
    12
  • cDNA Data
    20
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029370 Ensembl Gene Model | MGI Sequence Detail 37582 C57BL/6J ±  kb
transcript ENSMUST00000202704 Ensembl | MGI Sequence Detail 1178 Not Applicable  
polypeptide ENSMUSP00000144532 Ensembl | MGI Sequence Detail 341 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:330726 Morishita M, et al., Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-kappaB signaling. Genes Cells. 2021;26(12):999-1013
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory