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Fbxo47 Gene Detail
Summary
  • Symbol
    Fbxo47
  • Name
    F-box protein 47
  • Synonyms
    2900052P03Rik, LOC380724
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920223
    NCBI Gene: 72973
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97744652-97774980 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 61.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    785 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920223
 protein coding gene Chr11:97741137-97775240 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019044
 protein coding gene Chr11:100336131-100369583 (-)
A/J MGP_AJ_G0019012
 protein coding gene Chr11:96182682-96216377 (-)
AKR/J MGP_AKRJ_G0018982
 protein coding gene Chr11:99166870-99199507 (-)
BALB/cJ MGP_BALBcJ_G0018985
 protein coding gene Chr11:96682739-96714436 (-)
C3H/HeJ MGP_C3HHeJ_G0018799
 protein coding gene Chr11:99292831-99324086 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019438
 protein coding gene Chr11:103422647-103457182 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017069
 protein coding gene Chr11:93637221-93669144 (-)
CAST/EiJ MGP_CASTEiJ_G0018353
 protein coding gene Chr11:100159770-100197344 (-)
CBA/J MGP_CBAJ_G0018770
 protein coding gene Chr11:107708641-107746255 (-)
DBA/2J MGP_DBA2J_G0018878
 protein coding gene Chr11:95737483-95768062 (-)
FVB/NJ MGP_FVBNJ_G0018867
 protein coding gene Chr11:95232047-95261647 (-)
LP/J MGP_LPJ_G0018948
 protein coding gene Chr11:100828921-100861447 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018894
 protein coding gene Chr11:107529020-107567475 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019478
 protein coding gene Chr11:99476227-99513713 (-)
PWK/PhJ MGP_PWKPhJ_G0018125
 protein coding gene Chr11:96721672-96753498 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017915
 protein coding gene Chr11:99199846-99232151 (-)
WSB/EiJ MGP_WSBEiJ_G0018403
 protein coding gene Chr11:99382445-99417804 (-)



Homology
more
  • Human Ortholog
    FBXO47, F-box protein 47
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO47, F-box protein 47
  • Links
    NCBI Gene ID: 494188
    UniProt: Q5MNV8

  • Chr Location
    chr17:38936432-38967403 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility associated with premature synaptonemal complex disassembly leading to failed spermatogenesis.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000070336 Ensembl Gene Model | MGI Sequence Detail 30329 C57BL/6J ±  kb
    transcript ENSMUST00000093939 Ensembl | MGI Sequence Detail 2162 Not Applicable  
    polypeptide ENSMUSP00000091471 Ensembl | MGI Sequence Detail 451 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2686408
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 1
      Phenotypes 19
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:367586 Ma A, et al., FBXO47 regulates centromere pairing as key component of centromeric SCF E3 ligase in mouse spermatocytes. Commun Biol. 2024 Sep 7;7(1):1099
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/18/2025
    MGI 6.24     		The Jackson Laboratory