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Hepacam Gene Detail
Summary
  • Symbol
    Hepacam
  • Name
    hepatocyte cell adhesion molecule
  • Synonyms
    2900042E01Rik, Glialcam
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920177
    NCBI Gene: 72927
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:37278652-37297868 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 20.76 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    639 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920177
 protein coding gene Chr9:37278647-37297871 (+)
129S1/SvImJ ENSMUSG00200038648
 protein coding gene Chr9:34266017-34285204 (+)
A/J ENSMUSG00195048450
 protein coding gene Chr9:34052644-34071826 (+)
AKR/J ENSMUSG00220044512
 protein coding gene Chr9:34129247-34148428 (+)
BALB/cJ ENSMUSG00180043588
 protein coding gene Chr9:34180964-34200149 (+)
C3H/HeJ ENSMUSG00175041893
 protein coding gene Chr9:34181991-34201175 (+)
C57BL/6NJ ENSMUSG00215030372
 protein coding gene Chr9:34184504-34203733 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031980
 protein coding gene Chr9:33522089-33541397 (+)
CAST/EiJ ENSTCUG00005041916
 protein coding gene Chr9:34138612-34157640 (+)
CBA/J ENSMUSG00210042776
 protein coding gene Chr9:34170334-34189565 (+)
DBA/2J ENSMUSG00185032209
 protein coding gene Chr9:34278656-34297837 (+)
FVB/NJ ENSMUSG00205022238
 protein coding gene Chr9:34544252-34563448 (+)
JF1/MsJ ENSUMUG00000032627
 protein coding gene Chr9:34375334-34394831 (+)
LP/J ENSMUSG00230027610
 protein coding gene Chr9:34633145-34652652 (+)
NOD/ShiLtJ ENSMUSG00190029925
 protein coding gene Chr9:34303444-34322447 (+)
NZO/HlLtJ ENSMUSG00225020562
 protein coding gene Chr9:34601562-34621074 (+)
PWK/PhJ ENSLUMG00010039496
 protein coding gene Chr9:34316908-34336322 (+)
SPRET/EiJ ENSMSPG00010027909
 protein coding gene Chr9:34876209-34894398 (+)
WSB/EiJ ENSIUOG00005040868
 protein coding gene Chr9:33803489-33822686 (+)



Homology
more
  • Human Ortholog
    HEPACAM, hepatic and glial cell adhesion molecule
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HEPACAM, hepatic and glial cell adhesion molecule
  • Synonyms
    GlialCAM, MLC2A, MLC2B
  • Links
    NCBI Gene ID: 220296
    UniProt: Q14CZ8

  • Chr Location
    11q24.2; chr11:124919205-124936431 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Hepacam mouse models; 2 with human HEPACAM associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 3 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display myelin vacuolization that progresses with age.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    763
  • Tissues
    97
  • cDNA Data
    11
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72927 NCBI Gene Model | MGI Sequence Detail 19217 C57BL/6J ±  kb
    transcript NM_175189 RefSeq | MGI Sequence Detail 3103 C57BL/6  
    polypeptide Q640R3 UniProt | EBI | MGI Sequence Detail 418 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 11
      Primer pair 1
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 6
      Diseases 1
      Gene Ontology 7
      Phenotypes 16
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:389864 Murata K, et al., A novel miniTurbo knock-in mouse reveals a protein interaction network of USP46 in the brain. Exp Anim. 2026 Jan 1;75(1):63-72
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory