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Tmem216 Gene Detail
Summary
  • Symbol
    Tmem216
  • Name
    transmembrane protein 216
  • Synonyms
    1110017C22Rik, 2810441K11Rik, 4921533J23Rik, A930021F15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920020
    NCBI Gene: 68642
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10516690-10533663 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 6.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920020
 protein coding gene Chr19:10511229-10533663 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024848
 protein coding gene Chr19:7881035-7902865 (-)
A/J MGP_AJ_G0024816
 protein coding gene Chr19:7342769-7365478 (-)
AKR/J MGP_AKRJ_G0024791
 protein coding gene Chr19:7633064-7655461 (-)
BALB/cJ MGP_BALBcJ_G0024816
 protein coding gene Chr19:7386904-7409852 (-)
C3H/HeJ MGP_C3HHeJ_G0024582
 protein coding gene Chr19:7518641-7540502 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025264
 protein coding gene Chr19:8237419-8261497 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022691
 protein coding gene Chr19:7761566-7785519 (-)
CAST/EiJ MGP_CASTEiJ_G0024055
 protein coding gene Chr19:7172207-7195512 (-)
CBA/J MGP_CBAJ_G0024556
 protein coding gene Chr19:8282768-8305278 (-)
DBA/2J MGP_DBA2J_G0024683
 protein coding gene Chr19:7354409-7377367 (-)
FVB/NJ MGP_FVBNJ_G0024650
 protein coding gene Chr19:7397939-7421520 (-)
LP/J MGP_LPJ_G0024770
 protein coding gene Chr19:7844342-7867927 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024677
 protein coding gene Chr19:8173270-8209421 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025312
 protein coding gene Chr19:7651837-7675502 (-)
PWK/PhJ MGP_PWKPhJ_G0023800
 protein coding gene Chr19:6796829-6820044 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023605
 protein coding gene Chr19:6831267-6855487 (-)
WSB/EiJ MGP_WSBEiJ_G0024117
 protein coding gene Chr19:7533224-7557217 (-)



Homology
more
  • Human Ortholog
    TMEM216, transmembrane protein 216
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM216, transmembrane protein 216
  • Synonyms
    HSPC244
  • Links
    NCBI Gene ID: 51259
    neXtProt AC: NX_Q9P0N5
    UniProt: Q9P0N5

  • Chr Location
    11q12.2; chr11:61392393-61398866 (+)  GRCh38
Human Diseases
more
  • Diseases
    3 with human TMEM216 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    39
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68642 NCBI Gene Model | MGI Sequence Detail 16974 C57BL/6J ±  kb
transcript NM_026798 RefSeq | MGI Sequence Detail 1101 C57BL/6  
polypeptide Q9CQC4 UniProt | EBI | MGI Sequence Detail 141 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915892, MGI:1918182, MGI:1924512, MGI:2147568
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/19/2023
MGI 6.22 		The Jackson Laboratory