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Fam117b Gene Detail
Summary
  • Symbol
    Fam117b
  • Name
    family with sequence similarity 117, member B
  • Synonyms
    2810425F24Rik, 6330416D14Rik, Als2cr13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920000
    NCBI Gene: 72750
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:59952165-60024505 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 30.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1188 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920000
 protein coding gene Chr1:59952165-60024507 (+)
129S1/SvImJ ENSMUSG00200018097
 protein coding gene Chr1:57451785-57524132 (+)
A/J ENSMUSG00195027162
 protein coding gene Chr1:56991048-57063402 (+)
AKR/J ENSMUSG00220037093
 protein coding gene Chr1:57075238-57147647 (+)
BALB/cJ ENSMUSG00180013241
 protein coding gene Chr1:57225273-57297684 (+)
C3H/HeJ ENSMUSG00175000975
 protein coding gene Chr1:57368453-57440792 (+)
C57BL/6NJ ENSMUSG00215028502
 protein coding gene Chr1:57300335-57372680 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014183
 protein coding gene Chr1:54033402-54104022 (+)
CAST/EiJ ENSTCUG00005013134
 protein coding gene Chr1:57140785-57213276 (+)
CBA/J ENSMUSG00210031821
 protein coding gene Chr1:57053413-57125752 (+)
DBA/2J ENSMUSG00185039004
 protein coding gene Chr1:58173161-58245502 (+)
FVB/NJ ENSMUSG00205012953
 protein coding gene Chr1:57014274-57086623 (+)
JF1/MsJ ENSUMUG00000040159
 protein coding gene Chr1:57140951-57214090 (+)
LP/J ENSMUSG00230023783
 protein coding gene Chr1:58173677-58246018 (+)
NOD/ShiLtJ ENSMUSG00190024412
 protein coding gene Chr1:57211862-57284266 (+)
NZO/HlLtJ ENSMUSG00225008222
 protein coding gene Chr1:61380107-61452502 (+)
PWK/PhJ ENSLUMG00010024166
 protein coding gene Chr1:56651552-56724652 (+)
SPRET/EiJ ENSMSPG00010021880
 protein coding gene Chr1:58582690-58654386 (+)
WSB/EiJ ENSIUOG00005018377
 protein coding gene Chr1:56838995-56913535 (+)



Homology
more
  • Human Ortholog
    FAM117B, family with sequence similarity 117 member B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM117B, family with sequence similarity 117 member B
  • Synonyms
    ALS2CR13
  • Links
    NCBI Gene ID: 150864
    UniProt: Q6P1L5

  • Chr Location
    2q33.2; chr2:202634969-202769757 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    92
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041040 Ensembl Gene Model | MGI Sequence Detail 72341 C57BL/6J ±  kb
    transcript ENSMUST00000036540 Ensembl | MGI Sequence Detail 5532 Not Applicable  
    polypeptide ENSMUSP00000041671 Ensembl | MGI Sequence Detail 584 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000029455 protein FAM117B
      (term hierarchy)
    • InterPro Domains
      IPR026642 Glucocorticoid-induced transcript 1/FAM117
    • GlyGen
      Q3U3E2 7 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (5 sites)
    Molecular
    Reagents
    less
    • All nucleic 92
      cDNA 92

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1917984
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Phenotypes 12
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory