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Lime1 Gene Detail
Summary
  • Symbol
    Lime1
  • Name
    Lck interacting transmembrane adaptor 1
  • Synonyms
    2810038K19Rik, LIME
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919949
    NCBI Gene: 72699
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:181023028-181025421 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.63 cM, cytoband H4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919949
 protein coding gene Chr2:181021871-181025421 (+)
129S1/SvImJ ENSMUSG00200002410
 protein coding gene Chr2:177029754-177047980 (+)
A/J ENSMUSG00195001092
 protein coding gene Chr2:177261775-177279982 (+)
AKR/J ENSMUSG00220000072
 protein coding gene Chr2:174940408-174958613 (+)
BALB/cJ ENSMUSG00180000619
 protein coding gene Chr2:175069050-175087274 (+)
C3H/HeJ ENSMUSG00175004371
 protein coding gene Chr2:176222343-176240552 (+)
C57BL/6NJ ENSMUSG00215002494
 protein coding gene Chr2:175169248-175187471 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024807
 protein coding gene Chr2:170913949-170917495 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210001218
 protein coding gene Chr2:175547602-175565832 (+)
DBA/2J ENSMUSG00185020150
 protein coding gene Chr2:176781787-176799994 (+)
FVB/NJ no annotation
JF1/MsJ no annotation
LP/J ENSMUSG00230022819
 protein coding gene Chr2:178680688-178698914 (+)
NOD/ShiLtJ ENSMUSG00190015967
 protein coding gene Chr2:175089167-175107397 (+)
NZO/HlLtJ ENSMUSG00225006578
 protein coding gene Chr2:186763055-186781257 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPGG00010052277
 protein coding gene Chr2:177885036-177887423 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LIME1, Lck interacting transmembrane adaptor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LIME1, Lck interacting transmembrane adaptor 1
  • Synonyms
    dJ583P15.4, LIME
  • Links
    NCBI Gene ID: 54923
    UniProt: Q9H400

  • Chr Location
    20q13.33; chr20:63735701-63739106 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null allele exhibit no detectable abnormalities in the development and function of B and T cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    650
  • Tissues
    8
  • cDNA Data
    54
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72699 NCBI Gene Model | MGI Sequence Detail 2394 C57BL/6J ±  kb
transcript NM_023684 RefSeq | MGI Sequence Detail 1987 Not Specified  
polypeptide Q9EQR5 UniProt | EBI | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory