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Rab38 Gene Detail
Summary
  • Symbol
    Rab38
  • Name
    RAB38, member RAS oncogene family
  • Synonyms
    2310011F14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919683
    NCBI Gene: 72433
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:88079481-88140780 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 49.19 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1698 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919683
 protein coding gene Chr7:88079481-88140780 (+)
129S1/SvImJ ENSMUSG00200024909
 protein coding gene Chr7:74877735-74939069 (+)
A/J ENSMUSG00195037478
 protein coding gene Chr7:79407497-79468771 (+)
AKR/J ENSMUSG00220040274
 protein coding gene Chr7:72892459-72953732 (+)
BALB/cJ ENSMUSG00180036452
 protein coding gene Chr7:76084450-76145721 (+)
C3H/HeJ ENSMUSG00175035409
 protein coding gene Chr7:76772822-76834149 (+)
C57BL/6NJ ENSMUSG00215026444
 protein coding gene Chr7:75914861-75976165 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029971
 protein coding gene Chr7:91627906-91693632 (+)
CAST/EiJ ENSTCUG00005041905
 protein coding gene Chr7:79400999-79462648 (+)
CBA/J ENSMUSG00210034112
 protein coding gene Chr7:76615713-76677038 (+)
DBA/2J ENSMUSG00185032197
 protein coding gene Chr7:80945251-81006574 (+)
FVB/NJ ENSMUSG00205032453
 protein coding gene Chr7:76572422-76633704 (+)
JF1/MsJ ENSUMUG00000019343
 protein coding gene Chr7:85885292-85946693 (+)
LP/J ENSMUSG00230014358
 protein coding gene Chr7:87034885-87096210 (+)
NOD/ShiLtJ ENSMUSG00190028294
 protein coding gene Chr7:76828653-76889932 (+)
NZO/HlLtJ ENSMUSG00225009923
 protein coding gene Chr7:85309523-85370850 (+)
PWK/PhJ ENSLUMG00010035443
 protein coding gene Chr7:75072600-75134148 (+)
SPRET/EiJ ENSMSPG00010012560
 protein coding gene Chr7:76088996-76157422 (+)
WSB/EiJ ENSIUOG00005031646
 protein coding gene Chr7:77170754-77232066 (+)



Homology
more
  • Human Ortholog
    RAB38, RAB38, member RAS oncogene family
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB38, RAB38, member RAS oncogene family
  • Synonyms
    NY-MEL-1, rrGTPbp
  • Links
    NCBI Gene ID: 23682
    UniProt: P57729

  • Chr Location
    11q14.2; chr11:87803715-88175443 (-)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 5 alleles in 5 genetic backgrounds
    13 phenotypes from multigenic genotypes
    4 images
    39 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a spontaneous mutation display oculocutaneous albinism, abnormal lung alveolar structure and aberrant pulmonary surfactant homeostasis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    81
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    731
  • Tissues
    19
  • cDNA Data
    13
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72433 NCBI Gene Model | MGI Sequence Detail 61300 C57BL/6J ±  kb
    transcript NM_028238 RefSeq | MGI Sequence Detail 1577 C57BL/6  
    polypeptide Q8QZZ8 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 13
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-1982, MGI:2142161, MGI:88400
    References
    more
    • Summaries
      All 87
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 13
      Phenotypes 39
    • Earliest
      J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
    • Latest
      J:341218 Noda K, et al., Characterization of Rab32- and Rab38-positive lysosome-related organelles in osteoclasts and macrophages. J Biol Chem. 2023 Aug 23;299(10):105191
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory