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Ccdc74a Gene Detail
Summary
  • Symbol
    Ccdc74a
  • Name
    coiled-coil domain containing 74A
  • Synonyms
    2310015A05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919565
    NCBI Gene: 72315
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:17464340-17468602 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 10.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919565
 protein coding gene Chr16:17464334-17468602 (+)
129S1/SvImJ ENSMUSG00200042618
 protein coding gene Chr16:14460848-14465809 (+)
A/J ENSMUSG00195029093
 protein coding gene Chr16:14018134-14023095 (+)
AKR/J ENSMUSG00220042151
 protein coding gene Chr16:14334402-14339363 (+)
BALB/cJ ENSMUSG00180029613
 protein coding gene Chr16:14259371-14264332 (+)
C3H/HeJ ENSMUSG00175039169
 protein coding gene Chr16:14404385-14409346 (+)
C57BL/6NJ ENSMUSG00215040944
 protein coding gene Chr16:14125481-14130442 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020523
 protein coding gene Chr16:14134270-14138580 (+)
CAST/EiJ ENSTCUG00005044638
 protein coding gene Chr16:14334015-14339053 (+)
CBA/J ENSMUSG00210046320
 protein coding gene Chr16:14420700-14425661 (+)
DBA/2J ENSMUSG00185027391
 protein coding gene Chr16:14366844-14371805 (+)
FVB/NJ ENSMUSG00205027545
 protein coding gene Chr16:14374458-14379419 (+)
JF1/MsJ ENSUMUG00000050640
 protein coding gene Chr16:14450245-14455286 (+)
LP/J ENSMUSG00230039970
 protein coding gene Chr16:16944751-16949712 (+)
NOD/ShiLtJ ENSMUSG00190038102
 protein coding gene Chr16:14506749-14511710 (+)
NZO/HlLtJ ENSMUSG00225031835
 protein coding gene Chr16:20190558-20195519 (+)
PWK/PhJ ENSLUMG00010047855
 protein coding gene Chr16:14332430-14337468 (+)
SPRET/EiJ ENSMSPG00010039666
 protein coding gene Chr16:14350143-14354488 (+)
WSB/EiJ ENSIUOG00005038182
 protein coding gene Chr16:14500844-14505807 (+)



Homology
more
  • Human Ortholog
    CCDC74A, coiled-coil domain containing 74A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC74A, coiled-coil domain containing 74A
  • Links
    NCBI Gene ID: 90557
    UniProt: Q96AQ1

  • Chr Location
    2q21.1; chr2:131522592-131533666 (+)  GRCh38
  • Human Ortholog
    CCDC74B, coiled-coil domain containing 74B
  • Links
    NCBI Gene ID: 91409
    UniProt: Q96LY2

  • Chr Location
    2q21.1; chr2:130139287-130145134 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72315 NCBI Gene Model | MGI Sequence Detail 4263 C57BL/6J ±  kb
transcript NM_001166164 RefSeq | MGI Sequence Detail 1252 C57BL/6  
polypeptide NP_001159636 RefSeq | MGI Sequence Detail 364 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR039496 CCDC92/74, N-terminal
    IPR040370 Coiled-coil domain-containing protein 74A/74B/92
    IPR029422 Coiled coil protein 74, C-terminal
  • GlyGen
    E9Q9U8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Diseases 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:359574 Eom TY, et al., Tbx1 haploinsufficiency leads to local skull deformity, paraflocculus and flocculus dysplasia, and motor-learning deficit in 22q11.2 deletion syndrome. Nat Commun. 2024 Dec 5;15(1):10510
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory