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Klhl35 Gene Detail
Summary
  • Symbol
    Klhl35
  • Name
    kelch-like 35
  • Synonyms
    2810406K13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919434
    NCBI Gene: 72184
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:99115211-99123229 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.07 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    308 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919434
 protein coding gene Chr7:99112328-99123229 (+)
129S1/SvImJ ENSMUSG00200049425
 protein coding gene Chr7:85943732-85945510 (+)
A/J ENSMUSG00195037087
 protein coding gene Chr7:90449113-90450891 (+)
AKR/J ENSMUSG00220044517
 protein coding gene Chr7:83865766-83867544 (+)
BALB/cJ ENSMUSG00180032935
 protein coding gene Chr7:87122127-87123905 (+)
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215019049
 protein coding gene Chr7:86966926-86968704 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030028
 protein coding gene Chr7:102146455-102154478 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ ENSMUSG00205032822
 protein coding gene Chr7:87620287-87622065 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230038844
 protein coding gene Chr7:98069199-98070977 (+)
NOD/ShiLtJ ENSMUSG00190018101
 protein coding gene Chr7:87893910-87895688 (+)
NZO/HlLtJ ENSMUSG00225050534
 protein coding gene Chr7:96263822-96265600 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KLHL35, kelch like family member 35
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLHL35, kelch like family member 35
  • Links
    NCBI Gene ID: 283212
    UniProt: Q6PF15

  • Chr Location
    11q13.4; chr11:75422394-75433203 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    643
  • Tissues
    5
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035298 Ensembl Gene Model | MGI Sequence Detail 8019 C57BL/6J ±  kb
transcript ENSMUST00000037359 Ensembl | MGI Sequence Detail 1954 Not Applicable  
polypeptide ENSMUSP00000041363 Ensembl | MGI Sequence Detail 574 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory