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Trim29 Gene Detail
Summary
  • Symbol
    Trim29
  • Name
    tripartite motif-containing 29
  • Synonyms
    1110047J21Rik, 2810431N19Rik, 4732461M22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919419
    NCBI Gene: 72169
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:43222145-43247412 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 24.28 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    783 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919419
 protein coding gene Chr9:43222012-43247422 (+)
129S1/SvImJ ENSMUSG00200037737
 protein coding gene Chr9:40309993-40335263 (+)
A/J ENSMUSG00195044981
 protein coding gene Chr9:40053748-40078965 (+)
AKR/J ENSMUSG00220040495
 protein coding gene Chr9:40142639-40167873 (+)
BALB/cJ ENSMUSG00180043350
 protein coding gene Chr9:40165466-40190680 (+)
C3H/HeJ ENSMUSG00175046086
 protein coding gene Chr9:40177263-40202475 (+)
C57BL/6NJ ENSMUSG00215024575
 protein coding gene Chr9:40141594-40166861 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032092
 protein coding gene Chr9:40192599-40218389 (+)
CAST/EiJ ENSTCUG00005042827
 protein coding gene Chr9:40141729-40167011 (+)
CBA/J ENSMUSG00210043811
 protein coding gene Chr9:40225121-40250416 (+)
DBA/2J ENSMUSG00185034387
 protein coding gene Chr9:40292195-40317407 (+)
FVB/NJ ENSMUSG00205040041
 protein coding gene Chr9:40542191-40567416 (+)
JF1/MsJ ENSUMUG00000033625
 protein coding gene Chr9:40336426-40361752 (+)
LP/J ENSMUSG00230032111
 protein coding gene Chr9:40600650-40625917 (+)
NOD/ShiLtJ ENSMUSG00190020592
 protein coding gene Chr9:40371260-40396472 (+)
NZO/HlLtJ ENSMUSG00225042382
 protein coding gene Chr9:40554871-40580154 (+)
PWK/PhJ ENSLUMG00010045245
 protein coding gene Chr9:40303769-40329096 (+)
SPRET/EiJ ENSMSPG00010010680
 protein coding gene Chr9:41072742-41097114 (+)
WSB/EiJ ENSIUOG00005043619
 protein coding gene Chr9:39787847-39813068 (+)



Homology
more
  • Human Ortholog
    TRIM29, tripartite motif containing 29
  • Vertebrate Orthologs
    15
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM29, tripartite motif containing 29
  • Synonyms
    ATDC
  • Links
    NCBI Gene ID: 23650
    UniProt: Q14134

  • Chr Location
    11q23.3; chr11:120111286-120185529 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 3 alleles in 5 genetic backgrounds
    5 phenotypes from multigenic genotypes
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous inactivation of this gene protects male mice from Coxsackievirus B3-induced myocarditis by enhancing antiviral innate immunity, attenuating inflammation and cardiac damage, and improving cardiac function and survival rates. Primary neonatal cardiomyocytes from mice infected with cardiotropic viruses show reduced ER stress and apoptosis, decreased reactive oxygen species levels, and increased production of type I interferons.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    704
  • Tissues
    20
  • cDNA Data
    44
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032013 Ensembl Gene Model | MGI Sequence Detail 25268 C57BL/6J ±  kb
    transcript ENSMUST00000034511 Ensembl | MGI Sequence Detail 2735 Not Applicable  
    polypeptide ENSMUSP00000034511 Ensembl | MGI Sequence Detail 587 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 46
      cDNA 45
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1916090, MGI:1923499, MGI:2142983
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 4
      Gene Ontology 7
      Phenotypes 19
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:390780 Qasrawi F, et al., DeltaNP63 regulates epithelial stratification and differentiation in the murine ureter. Am J Physiol Renal Physiol. 2026 Aug 1;331(2):F286-F303
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory