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Tdrp Gene Detail
Summary
  • Symbol
    Tdrp
  • Name
    testis development related protein
  • Synonyms
    2610019F03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919398
    NCBI Gene: 72148
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:14002008-14025032 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 6.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    966 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919398
 protein coding gene Chr8:14002008-14025484 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033392
 protein coding gene Chr8:11324998-11347467 (-)
A/J MGP_AJ_G0033373
 protein coding gene Chr8:10923879-10949993 (-)
AKR/J MGP_AKRJ_G0033303
 protein coding gene Chr8:11198036-11220384 (-)
BALB/cJ MGP_BALBcJ_G0033373
 protein coding gene Chr8:11029739-11052734 (-)
C3H/HeJ MGP_C3HHeJ_G0033086
 protein coding gene Chr8:11431985-11458098 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033885
 protein coding gene Chr8:11701852-11724230 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030852
 protein coding gene Chr8:10358833-10380877 (-)
CAST/EiJ MGP_CASTEiJ_G0032408
 protein coding gene Chr8:11215291-11241982 (-)
CBA/J MGP_CBAJ_G0033059
 protein coding gene Chr8:12192045-12218218 (-)
DBA/2J MGP_DBA2J_G0033213
 protein coding gene Chr8:10862860-10885713 (-)
FVB/NJ MGP_FVBNJ_G0033161
 protein coding gene Chr8:10876235-10901784 (-)
LP/J MGP_LPJ_G0033306
 protein coding gene Chr8:11294823-11326284 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033198
 protein coding gene Chr8:12438673-12461026 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033902
 protein coding gene Chr8:11295931-11319100 (-)
PWK/PhJ MGP_PWKPhJ_G0032121
 protein coding gene Chr8:10917374-10941999 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031962
 protein coding gene Chr8:11155911-11177619 (-)
WSB/EiJ MGP_WSBEiJ_G0032524
 protein coding gene Chr8:11317944-11342724 (-)



Homology
more
  • Human Ortholog
    TDRP, testis development related protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TDRP, testis development related protein
  • Synonyms
    C8orf42, Inm01, TDRP1, TDRP2
  • Links
    NCBI Gene ID: 157695
    UniProt: Q86YL5

  • Chr Location
    8p23.3; chr8:489803-545781 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Null males exhibit impaired sperm motility but normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    841
  • Tissues
    98
  • cDNA Data
    73
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000050052 Ensembl Gene Model | MGI Sequence Detail 23025 C57BL/6J ±  kb
    transcript ENSMUST00000062613 Ensembl | MGI Sequence Detail 2463 Not Applicable  
    polypeptide ENSMUSP00000058371 Ensembl | MGI Sequence Detail 182 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 73
      cDNA 73

      Microarray probesets 3
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/18/2025
    MGI 6.24     		The Jackson Laboratory