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Tedc2 Gene Detail
Summary
  • Symbol
    Tedc2
  • Name
    tubulin epsilon and delta complex 2
  • Synonyms
    1600002H07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919266
    NCBI Gene: 72016
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24434028-24439825 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.32 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    273 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919266
 protein coding gene Chr17:24434028-24439825 (-)
129S1/SvImJ ENSMUSG00200038137
 protein coding gene Chr17:19866479-19872225 (-)
A/J ENSMUSG00195053998
 protein coding gene Chr17:20885291-20891037 (-)
AKR/J ENSMUSG00220024525
 protein coding gene Chr17:19944156-19949901 (-)
BALB/cJ ENSMUSG00180042633
 protein coding gene Chr17:20168116-20173849 (-)
C3H/HeJ ENSMUSG00175035774
 protein coding gene Chr17:19921845-19927592 (-)
C57BL/6NJ ENSMUSG00215040146
 protein coding gene Chr17:19941970-19947706 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021178
 protein coding gene Chr17:20025560-20031516 (-)
CAST/EiJ ENSTCUG00005047323
 protein coding gene Chr17:20512150-20517878 (-)
CBA/J ENSMUSG00210030996
 protein coding gene Chr17:19760684-19766432 (-)
DBA/2J ENSMUSG00185047664
 protein coding gene Chr17:21973646-21979392 (-)
FVB/NJ ENSMUSG00205025731
 protein coding gene Chr17:20235324-20241063 (-)
JF1/MsJ ENSUMUG00000056935
 protein coding gene Chr17:21433786-21439522 (-)
LP/J ENSMUSG00230054920
 protein coding gene Chr17:23371150-23376896 (-)
NOD/ShiLtJ ENSMUSG00190031634
 protein coding gene Chr17:19862384-19868130 (-)
NZO/HlLtJ ENSMUSG00225052310
 protein coding gene Chr17:25292772-25298518 (-)
PWK/PhJ ENSLUMG00010018772
 protein coding gene Chr17:19345627-19351368 (-)
SPRET/EiJ ENSMSPG00010040387
 protein coding gene Chr17:20680480-20685471 (-)
WSB/EiJ ENSIUOG00005050289
 protein coding gene Chr17:20620760-20626502 (-)



Homology
more
  • Human Ortholog
    TEDC2, tubulin epsilon and delta complex 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEDC2, tubulin epsilon and delta complex 2
  • Synonyms
    C16orf59
  • Links
    NCBI Gene ID: 80178
    UniProt: Q7L2K0

  • Chr Location
    16p13.3; chr16:2460086-2464963 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotypes from 1 allele in 1 genetic background
    5 images
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele lack a properly patterned ventral neural tube and exhibit incomplete rostral neuropore closure, caudal neural tube kinks, failure of embryo turning, absence of the notochord in some portions of the embryo, abnormal head and heart shape, cardiac edema, and complete lethality during organogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    615
  • Tissues
    14
  • cDNA Data
    38
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72016 NCBI Gene Model | MGI Sequence Detail 5798 C57BL/6J ±  kb
    transcript NM_028056 RefSeq | MGI Sequence Detail 2261 C57BL/6  
    polypeptide Q6GQV0 UniProt | EBI | MGI Sequence Detail 436 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000036976 tubulin epsilon and delta complex protein 2
      (term hierarchy)
    • InterPro Domains
      IPR031518 Protein of unknown function DUF4693
    • GlyGen
      Q6GQV0 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 38
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:5904756
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory