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Acad10 Gene Detail
Summary
  • Symbol
    Acad10
  • Name
    acyl-Coenzyme A dehydrogenase family, member 10
  • Synonyms
    2410021P16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919235
    NCBI Gene: 71985
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:121759089-121798577 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 61.88 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    224 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919235
protein coding gene Chr5:121759089-121798642 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030035
protein coding gene Chr5:125132770-125206692 (-)
A/J MGP_AJ_G0030000
protein coding gene Chr5:119999408-120043196 (-)
AKR/J MGP_AKRJ_G0029936
protein coding gene Chr5:123855067-123908605 (-)
BALB/cJ MGP_BALBcJ_G0030011
protein coding gene Chr5:121354329-121402067 (-)
C3H/HeJ MGP_C3HHeJ_G0029728
protein coding gene Chr5:124430298-124503416 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030464
protein coding gene Chr5:129939178-129973495 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027690
protein coding gene Chr5:114648186-114688938 (-)
CAST/EiJ MGP_CASTEiJ_G0029137
protein coding gene Chr5:123540138-123594144 (-)
CBA/J MGP_CBAJ_G0029698
protein coding gene Chr5:135015483-135092974 (-)
DBA/2J MGP_DBA2J_G0029848
protein coding gene Chr5:120047663-120099282 (-)
FVB/NJ MGP_FVBNJ_G0029804
protein coding gene Chr5:119006619-119077047 (-)
LP/J MGP_LPJ_G0029937
protein coding gene Chr5:125658057-125731699 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029835
protein coding gene Chr5:138848782-138925506 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030505
protein coding gene Chr5:123370523-123463140 (-)
PWK/PhJ MGP_PWKPhJ_G0028851
protein coding gene Chr5:118818329-118865075 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028688
protein coding gene Chr5:121166280-121172632 (-)
WSB/EiJ MGP_WSBEiJ_G0029212
protein coding gene Chr5:124027933-124088818 (-)



Homology
more
  • Human Ortholog
    ACAD10, acyl-CoA dehydrogenase family member 10
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACAD10, acyl-CoA dehydrogenase family member 10
  • Links
    NCBI Gene ID: 80724
    neXtProt AC: NX_Q6JQN1
    UniProt: Q6JQN1

  • Chr Location
    12q24.12; chr12:111686053-111757107 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029456 Ensembl Gene Model | MGI Sequence Detail 39489 C57BL/6J ±  kb
    transcript ENSMUST00000031412 Ensembl | MGI Sequence Detail 3826 Not Applicable  
    polypeptide ENSMUSP00000031412 Ensembl | MGI Sequence Detail 1069 Not Applicable  
    For the selected sequence
    Protein
    Information
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    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000032794 acyl-CoA dehydrogenase family member 10
    • EC
    • InterPro Domains
      IPR041726 Acyl-CoA dehydrogenase family member 10/11, N-terminal
      IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
      IPR009075 Acyl-CoA dehydrogenase/oxidase, C-terminal
      IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
      IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
      IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
      IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain
      IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
      IPR002575 Aminoglycoside phosphotransferase
      IPR006439 HAD hydrolase, subfamily IA
      IPR036412 HAD-like superfamily
      IPR023214 HAD superfamily
      IPR023198 Phosphoglycolate phosphatase-like, domain 2
      IPR011945 Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal
      IPR011009 Protein kinase-like domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 30
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 39
      Gene Ontology 4
      Phenotypes 15
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:344833 Shim SM, et al., The Cys-N-degron pathway modulates pexophagy through the N-terminal oxidation and arginylation of ACAD10. Autophagy. 2023 Jun;19(6):1642-1661

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    04/16/2024
    MGI 6.23
    The Jackson Laboratory