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Apol6 Gene Detail
Summary
  • Symbol
    Apol6
  • Name
    apolipoprotein L 6
  • Synonyms
    2310076O14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919189
    NCBI Gene: 71939
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76929195-76941308 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 36.39 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    95 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919189
 protein coding gene Chr15:76928929-76941308 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022020
 protein coding gene Chr15:77187241-77199437 (+)
A/J MGP_AJ_G0021978
 protein coding gene Chr15:74328401-74340974 (+)
AKR/J MGP_AKRJ_G0021961
 protein coding gene Chr15:76354154-76375361 (+)
BALB/cJ MGP_BALBcJ_G0021987
 protein coding gene Chr15:74352278-74364945 (+)
C3H/HeJ MGP_C3HHeJ_G0021759
 protein coding gene Chr15:76397422-76413138 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022427
 protein coding gene Chr15:80055893-80067466 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019956
 protein coding gene Chr15:70979373-70989441 (+)
CAST/EiJ MGP_CASTEiJ_G0021278
 protein coding gene Chr15:77204602-77218684 (+)
CBA/J MGP_CBAJ_G0021726
 protein coding gene Chr15:82589043-82602206 (+)
DBA/2J MGP_DBA2J_G0021851
 protein coding gene Chr15:73872223-73884399 (+)
FVB/NJ MGP_FVBNJ_G0021831
 protein coding gene Chr15:72928141-72941227 (+)
LP/J MGP_LPJ_G0021922
 protein coding gene Chr15:77248901-77263546 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021856
 protein coding gene Chr15:87904536-87916837 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022447
 protein coding gene Chr15:76623852-76636366 (+)
PWK/PhJ MGP_PWKPhJ_G0021019
 protein coding gene Chr15:74040799-74053337 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020859
 protein coding gene Chr15:76340865-76353816 (+)
WSB/EiJ MGP_WSBEiJ_G0021330
 protein coding gene Chr15:76729271-76742074 (+)



Homology
more
  • Human Ortholog
    APOL6, apolipoprotein L6
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    APOL6, apolipoprotein L6
  • Synonyms
    APOLVI, APOL-VI
  • Links
    NCBI Gene ID: 80830
    neXtProt AC: NX_Q9BWW8
    UniProt: Q9BWW8

  • Chr Location
    22q12.3; chr22:35648317-35668409 (+)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    26
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71939 NCBI Gene Model | MGI Sequence Detail 12114 C57BL/6J ±  kb
transcript NM_028010 RefSeq | MGI Sequence Detail 2325 C57BL/6  
polypeptide NP_001157093 RefSeq | MGI Sequence Detail 329 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR008405 Apolipoprotein L
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 2
References
more
  • Summaries
    All 46
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:319888 Son JS, et al., Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling. EBioMedicine. 2022 Jan 23;76:103842
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/21/2023
MGI 6.22 		The Jackson Laboratory