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Spmap2l Gene Detail
Summary
  • Symbol
    Spmap2l
  • Name
    sperm microtubule associated protein 2 like
  • Synonyms
    1700023E05Rik, Thegl
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919118
    NCBI Gene: 71868
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:77163879-77209382 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 41.45 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1270 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919118
 protein coding gene Chr5:77163870-77209382 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029653
 protein coding gene Chr5:77232791-77278023 (+)
A/J MGP_AJ_G0029621
 protein coding gene Chr5:74279159-74323854 (+)
AKR/J MGP_AKRJ_G0029569
 protein coding gene Chr5:76702828-76750923 (+)
BALB/cJ MGP_BALBcJ_G0029630
 protein coding gene Chr5:75015415-75059444 (+)
C3H/HeJ MGP_C3HHeJ_G0029353
 protein coding gene Chr5:77076098-77122090 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030084
 protein coding gene Chr5:80323705-80374583 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027325
 protein coding gene Chr5:69909401-69950512 (+)
CAST/EiJ MGP_CASTEiJ_G0028761
 protein coding gene Chr5:76286923-76335175 (+)
CBA/J MGP_CBAJ_G0029322
 protein coding gene Chr5:82966508-83019130 (+)
DBA/2J MGP_DBA2J_G0029467
 protein coding gene Chr5:74343971-74385608 (+)
FVB/NJ MGP_FVBNJ_G0029428
 protein coding gene Chr5:73539820-73585299 (+)
LP/J MGP_LPJ_G0029554
 protein coding gene Chr5:77669904-77716441 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029456
 protein coding gene Chr5:86097131-86148941 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030117
 protein coding gene Chr5:76254491-76300289 (+)
PWK/PhJ MGP_PWKPhJ_G0028484
 protein coding gene Chr5:73357026-73400261 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028319
 protein coding gene Chr5:75610922-75659716 (+)
WSB/EiJ MGP_WSBEiJ_G0028841
 protein coding gene Chr5:76585048-76630134 (+)



Homology
more
  • Human Ortholog
    SPMAP2L, sperm microtubule associated protein 2 like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPMAP2L, sperm microtubule associated protein 2 like
  • Synonyms
    THEGL
  • Links
    NCBI Gene ID: 100506564
    UniProt: P0DJG4

  • Chr Location
    chr4:56530606-56626214 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable and display normal male fertility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    5
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71868 NCBI Gene Model | MGI Sequence Detail 45504 C57BL/6J ±  kb
    transcript NM_027970 RefSeq | MGI Sequence Detail 1723 C57BL/6  
    polypeptide Q9DA15 UniProt | EBI | MGI Sequence Detail 459 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:7481231
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Phenotypes 11
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/18/2025
    MGI 6.24     		The Jackson Laboratory