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Vwce Gene Detail
Summary
  • Symbol
    Vwce
  • Name
    von Willebrand factor C and EGF domains
  • Synonyms
    1300015B04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919018
    NCBI Gene: 71768
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10611582-10643577 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 6.87 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1009 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919018
 protein coding gene Chr19:10611577-10643577 (+)
129S1/SvImJ ENSMUSG00200048908
 protein coding gene Chr19:7290489-7322470 (+)
A/J ENSMUSG00195045956
 protein coding gene Chr19:7500835-7533166 (+)
AKR/J ENSMUSG00220048144
 protein coding gene Chr19:7410991-7443314 (+)
BALB/cJ ENSMUSG00180049081
 protein coding gene Chr19:7864828-7897152 (+)
C3H/HeJ ENSMUSG00175010126
 protein coding gene Chr19:7138476-7170775 (+)
C57BL/6NJ ENSMUSG00215044566
 protein coding gene Chr19:7207814-7239794 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022696
 protein coding gene Chr19:7865459-7897791 (+)
CAST/EiJ ENSTCUG00005025923
 protein coding gene Chr19:7005148-7036735 (+)
CBA/J ENSMUSG00210048216
 protein coding gene Chr19:7337057-7369358 (+)
DBA/2J ENSMUSG00185051158
 protein coding gene Chr19:7746773-7779078 (+)
FVB/NJ ENSMUSG00205019043
 protein coding gene Chr19:7229052-7260918 (+)
JF1/MsJ ENSUMUG00000055455
 protein coding gene Chr19:7866441-7898546 (+)
LP/J ENSMUSG00230054095
 protein coding gene Chr19:8665157-8697136 (+)
NOD/ShiLtJ ENSMUSG00190037019
 protein coding gene Chr19:6962725-6995031 (+)
NZO/HlLtJ ENSMUSG00225045373
 protein coding gene Chr19:12374003-12405976 (+)
PWK/PhJ ENSLUMG00010006940
 protein coding gene Chr19:7250646-7282679 (+)
SPRET/EiJ ENSMSPG00010048021
 protein coding gene Chr19:7089219-7120980 (+)
WSB/EiJ ENSIUOG00005049955
 protein coding gene Chr19:6855775-6887739 (+)



Homology
more
  • Human Ortholog
    VWCE, von Willebrand factor C and EGF domains
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VWCE, von Willebrand factor C and EGF domains
  • Synonyms
    URG11, VWC1
  • Links
    NCBI Gene ID: 220001
    UniProt: Q96DN2

  • Chr Location
    11q12.2; chr11:61255672-61295334 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    651
  • Tissues
    8
  • cDNA Data
    13
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71768 NCBI Gene Model | MGI Sequence Detail 31996 C57BL/6J ±  kb
    transcript NM_027913 RefSeq | MGI Sequence Detail 4543 C57BL/6  
    polypeptide Q3U515 UniProt | EBI | MGI Sequence Detail 929 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 2
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory