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Rarres2 Gene Detail
Summary
  • Symbol
    Rarres2
  • Name
    retinoic acid receptor responder (tazarotene induced) 2
  • Synonyms
    0610007L05Rik, chemerin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918910
    NCBI Gene: 71660
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:48546630-48549723 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 23.55 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918910
protein coding gene Chr6:48546630-48549778 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030697
protein coding gene Chr6:47519782-47522875 (-)
A/J MGP_AJ_G0030668
protein coding gene Chr6:45359340-45362437 (-)
AKR/J MGP_AKRJ_G0030593
protein coding gene Chr6:46953494-46956591 (-)
BALB/cJ MGP_BALBcJ_G0030678
protein coding gene Chr6:45689948-45693045 (-)
C3H/HeJ MGP_C3HHeJ_G0030391
protein coding gene Chr6:46958125-46961222 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031133
protein coding gene Chr6:48638185-48641278 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028340
protein coding gene Chr6:42988992-42992610 (-)
CAST/EiJ MGP_CASTEiJ_G0029795
protein coding gene Chr6:46681441-46684528 (-)
CBA/J MGP_CBAJ_G0030366
protein coding gene Chr6:50652524-50655621 (-)
DBA/2J MGP_DBA2J_G0030515
protein coding gene Chr6:45275726-45278823 (-)
FVB/NJ MGP_FVBNJ_G0030467
protein coding gene Chr6:44905684-44908781 (-)
LP/J MGP_LPJ_G0030600
protein coding gene Chr6:47498724-47501817 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030501
protein coding gene Chr6:53466269-53469366 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031162
protein coding gene Chr6:46823705-46826798 (-)
PWK/PhJ MGP_PWKPhJ_G0029507
protein coding gene Chr6:44809488-44812585 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029343
protein coding gene Chr6:46172848-46175963 (-)
WSB/EiJ MGP_WSBEiJ_G0029872
protein coding gene Chr6:46820568-46823672 (-)



Homology
more
  • Human Ortholog
    RARRES2, retinoic acid receptor responder 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RARRES2, retinoic acid receptor responder 2
  • Synonyms
    HP10433, TIG2
  • Links
    NCBI Gene ID: 5919
    neXtProt AC: NX_Q99969
    UniProt: Q99969

  • Chr Location
    7q36.1; chr7:150338317-150341662 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit impaired glucose tolerance, impaired glucose-stimulated insulin secretion and increased clamp hepatic glucose production.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000009281 Ensembl Gene Model | MGI Sequence Detail 3094 C57BL/6J ±  kb
    transcript ENSMUST00000009425 Ensembl | MGI Sequence Detail 731 Not Applicable  
    polypeptide ENSMUSP00000009425 Ensembl | MGI Sequence Detail 163 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1889806
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 6
      Gene Ontology 9
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:342422 Lin X, et al., Aerobic exercise-induced decrease of chemerin improved glucose and lipid metabolism and fatty liver of diabetes mice through key metabolism enzymes and proteins. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Dec;1868(12):159409

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    05/28/2024
    MGI 6.13
    The Jackson Laboratory