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Armh3 Gene Detail
Summary
  • Symbol
    Armh3
  • Name
    armadillo-like helical domain containing 3
  • Synonyms
    9130011E15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918867
    NCBI Gene: 71617
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:45805803-45986927 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 38.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1283 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918867
 protein coding gene Chr19:45805799-45987071 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025195
 protein coding gene Chr19:45448921-45652448 (-)
A/J MGP_AJ_G0025171
 protein coding gene Chr19:43221486-43410200 (-)
AKR/J MGP_AKRJ_G0025140
 protein coding gene Chr19:44614681-44815833 (-)
BALB/cJ MGP_BALBcJ_G0025166
 protein coding gene Chr19:43282217-43463422 (-)
C3H/HeJ MGP_C3HHeJ_G0024926
 protein coding gene Chr19:44793010-44980886 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025609
 protein coding gene Chr19:46577423-46789603 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023023
 protein coding gene Chr19:42467791-42648864 (-)
CAST/EiJ MGP_CASTEiJ_G0024391
 protein coding gene Chr19:44553907-44754221 (-)
CBA/J MGP_CBAJ_G0024906
 protein coding gene Chr19:48922904-49138269 (-)
DBA/2J MGP_DBA2J_G0025038
 protein coding gene Chr19:43030418-43226050 (-)
FVB/NJ MGP_FVBNJ_G0024999
 protein coding gene Chr19:42822629-43003943 (-)
LP/J MGP_LPJ_G0025124
 protein coding gene Chr19:45354481-45557112 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025030
 protein coding gene Chr19:48270605-48498757 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025667
 protein coding gene Chr19:44712512-44910769 (-)
PWK/PhJ MGP_PWKPhJ_G0024140
 protein coding gene Chr19:42966619-43157892 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023944
 protein coding gene Chr19:43383968-43579150 (-)
WSB/EiJ MGP_WSBEiJ_G0024461
 protein coding gene Chr19:44858337-45058737 (-)



Homology
more
  • Human Ortholog
    ARMH3, armadillo like helical domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARMH3, armadillo like helical domain containing 3
  • Synonyms
    C10orf76
  • Links
    NCBI Gene ID: 79591
    neXtProt AC: NX_Q5T2E6
    UniProt: Q5T2E6

  • Chr Location
    10q24.32; chr10:101845599-102056193 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit defects in chorion and trophoblast layer formation and complete embryonic lethality during organogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    32
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039901 Ensembl Gene Model | MGI Sequence Detail 181125 C57BL/6J ±  kb
    transcript ENSMUST00000045396 Ensembl | MGI Sequence Detail 3676 Not Applicable  
    polypeptide ENSMUSP00000048454 Ensembl | MGI Sequence Detail 689 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000059823 armadillo-like helical domain-containing protein 3
      (term hierarchy)
    • InterPro Domains
      IPR013636 Armadillo-like helical domain-containing protein 3, C-terminal
      IPR039868 Armadillo-like helical domain-containing protein 3-like
      IPR016024 Armadillo-type fold
    Molecular
    Reagents
    less
    • All nucleic 33
      cDNA 32
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2147534, MGI:2147696
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:336776 Fang R, et al., ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING. Immunity. 2023 Mar 14;56(3):500-515.e6
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/26/2023
    MGI 6.22     		The Jackson Laboratory