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Snx20 Gene Detail
Summary
  • Symbol
    Snx20
  • Name
    sorting nexin 20
  • Synonyms
    9130017C17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918857
    NCBI Gene: 71607
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:89353191-89362756 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, 43.51 cM, cytoband C4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    387 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918857
protein coding gene Chr8:89353189-89362769 (-)
129S1/SvImJ ENSMUSG00200016066
protein coding gene Chr8:83709324-83718822 (-)
A/J ENSMUSG00195025636
protein coding gene Chr8:84080256-84089811 (-)
AKR/J ENSMUSG00220038911
protein coding gene Chr8:84108332-84117832 (-)
BALB/cJ ENSMUSG00180022224
protein coding gene Chr8:83912908-83922408 (-)
C3H/HeJ ENSMUSG00175025053
protein coding gene Chr8:84019095-84028647 (-)
C57BL/6NJ ENSMUSG00215021522
protein coding gene Chr8:83620512-83630069 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031359
protein coding gene Chr8:80159450-80168451 (-)
CAST/EiJ ENSTCUG00005016291
protein coding gene Chr8:83481893-83491361 (-)
CBA/J ENSMUSG00210031949
protein coding gene Chr8:83984264-83993740 (-)
DBA/2J ENSMUSG00185037550
protein coding gene Chr8:90092853-90102329 (-)
FVB/NJ ENSMUSG00205015448
protein coding gene Chr8:83040082-83049558 (-)
JF1/MsJ ENSUMUG00000031869
protein coding gene Chr8:92414492-92424066 (-)
LP/J ENSMUSG00230026825
protein coding gene Chr8:93706061-93715559 (-)
NOD/ShiLtJ ENSMUSG00190014809
protein coding gene Chr8:84073513-84083011 (-)
NZO/HlLtJ ENSMUSG00225038882
protein coding gene Chr8:97110140-97119638 (-)
PWK/PhJ ENSLUMG00010037594
protein coding gene Chr8:83725139-83734663 (-)
SPRET/EiJ ENSMSPG00010025249
protein coding gene Chr8:85664840-85673987 (-)
WSB/EiJ ENSIUOG00005019047
protein coding gene Chr8:84804927-84814401 (-)



Homology
more
  • Human Ortholog
    SNX20, sorting nexin 20
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNX20, sorting nexin 20
  • Synonyms
    SLIC1
  • Links
    NCBI Gene ID: 124460
    UniProt: Q7Z614

  • Chr Location
    16q12.1; chr16:50666300-50681743 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    32 phenotype references
Homozygous null mice are viable and healthy with no apparent defects in neutrophil morphology or physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031662 Ensembl Gene Model | MGI Sequence Detail 9566 C57BL/6J ±  kb
transcript ENSMUST00000034087 Ensembl | MGI Sequence Detail 1699 Not Applicable  
polypeptide ENSMUSP00000034087 Ensembl | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 3
References
more
  • Summaries
    All 59
    Gene Ontology 7
    Phenotypes 32
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:348117 Okuma H, et al., N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on alpha-dystroglycan and prevents muscular dystrophy. Elife. 2023 Feb 1;12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory