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Izumo4 Gene Detail
Summary
  • Symbol
    Izumo4
  • Name
    IZUMO family member 4
  • Synonyms
    9030607L17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918814
    NCBI Gene: 71564
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80538018-80541207 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    108 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918814
protein coding gene Chr10:80537858-80541216 (+)
129S1/SvImJ ENSMUSG00200043099
protein coding gene Chr10:77163975-77170128 (+)
A/J ENSMUSG00195041566
protein coding gene Chr10:77559547-77565700 (+)
AKR/J ENSMUSG00220047414
protein coding gene Chr10:77157233-77163386 (+)
BALB/cJ ENSMUSG00180046409
protein coding gene Chr10:77570011-77576164 (+)
C3H/HeJ ENSMUSG00175046286
protein coding gene Chr10:77440777-77446930 (+)
C57BL/6NJ ENSMUSG00215051927
protein coding gene Chr10:77182614-77188767 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015598
protein coding gene Chr10:74700473-74703118 (+)
CAST/EiJ ENSTCUG00005046228
protein coding gene Chr10:77068268-77074427 (+)
CBA/J ENSMUSG00210045021
protein coding gene Chr10:77296814-77302967 (+)
DBA/2J ENSMUSG00185050030
protein coding gene Chr10:77639230-77645383 (+)
FVB/NJ ENSMUSG00205037037
protein coding gene Chr10:77352023-77358176 (+)
JF1/MsJ ENSUMUG00000052367
protein coding gene Chr10:78869733-78875891 (+)
LP/J ENSMUSG00230050029
protein coding gene Chr10:79408856-79415009 (+)
NOD/ShiLtJ ENSMUSG00190049629
protein coding gene Chr10:77552954-77559107 (+)
NZO/HlLtJ ENSMUSG00225050825
protein coding gene Chr10:83695358-83701511 (+)
PWK/PhJ ENSLUMG00010038219
protein coding gene Chr10:77230657-77236815 (+)
SPRET/EiJ ENSMSPG00010042254
protein coding gene Chr10:78847173-78853275 (+)
WSB/EiJ ENSIUOG00005043813
protein coding gene Chr10:77256484-77262541 (+)



Homology
more
  • Human Ortholog
    IZUMO4, IZUMO family member 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IZUMO4, IZUMO family member 4
  • Synonyms
    C19orf36, IMAGE:4215339
  • Links
    NCBI Gene ID: 113177
    UniProt: Q1ZYL8

  • Chr Location
    19p13.3; chr19:2096429-2099593 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Mice homozygous for a knock-out allele exhibit normal fertility; adult males show no significant changes in relative testis weight, sperm morphology, testis and epididymis histology, or sperm motility parameters.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055862 Ensembl Gene Model | MGI Sequence Detail 3190 C57BL/6J ±  kb
transcript ENSMUST00000218184 Ensembl | MGI Sequence Detail 1196 Not Applicable  
polypeptide ENSMUSP00000151397 Ensembl | MGI Sequence Detail 227 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143641
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:385300 Chang HY, et al., Mouse genome engineering uncovers 18 genes dispensable for male reproduction. Andrology. 2026 Mar;14(3):833-846

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory