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Kctd6 Gene Detail
Summary
  • Symbol
    Kctd6
  • Name
    potassium channel tetramerisation domain containing 6
  • Synonyms
    5430433B02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918643
    NCBI Gene: 71393
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:14246186-14255692 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 4.76 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918643
 protein coding gene Chr14:14246186-14255878 (-)
129S1/SvImJ ENSMUSG00200013218
 protein coding gene Chr14:10886240-10895882 (-)
A/J ENSMUSG00195017896
 protein coding gene Chr14:11754059-11763729 (-)
AKR/J ENSMUSG00220023879
 protein coding gene Chr14:10918023-10927688 (-)
BALB/cJ ENSMUSG00180035997
 protein coding gene Chr14:11044864-11054532 (-)
C3H/HeJ ENSMUSG00175022304
 protein coding gene Chr14:11107972-11117658 (-)
C57BL/6NJ ENSMUSG00215029733
 protein coding gene Chr14:11293922-11303590 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018943
 protein coding gene Chr14:1444179-1453629 (+)
CAST/EiJ ENSTCUG00005026738
 protein coding gene Chr14:10925787-10935497 (-)
CBA/J ENSMUSG00210026442
 protein coding gene Chr14:11323025-11332713 (-)
DBA/2J ENSMUSG00185037758
 protein coding gene Chr14:11331480-11341166 (-)
FVB/NJ ENSMUSG00205025985
 protein coding gene Chr14:11243535-11253225 (-)
JF1/MsJ ENSUMUG00000018526
 protein coding gene Chr14:11265688-11275322 (-)
LP/J ENSMUSG00230012014
 protein coding gene Chr14:12383556-12393934 (-)
NOD/ShiLtJ ENSMUSG00190032024
 protein coding gene Chr14:11331742-11341429 (-)
NZO/HlLtJ ENSMUSG00225035512
 protein coding gene Chr14:11691186-11700865 (-)
PWK/PhJ ENSLUMG00010034516
 protein coding gene Chr14:32588984-32598646 (-)
SPRET/EiJ ENSMSPG00010028689
 protein coding gene Chr14:11731729-11741309 (-)
WSB/EiJ ENSIUOG00005031008
 protein coding gene Chr14:11174851-11184512 (-)



Homology
more
  • Human Ortholog
    KCTD6, potassium channel tetramerization domain containing 6
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCTD6, potassium channel tetramerization domain containing 6
  • Synonyms
    KCASH3
  • Links
    NCBI Gene ID: 200845
    UniProt: Q8NC69

  • Chr Location
    3p14.3; chr3:58491078-58502360 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    645
  • Tissues
    8
  • cDNA Data
    33
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71393 NCBI Gene Model | MGI Sequence Detail 9507 C57BL/6J ±  kb
transcript NM_001305936 RefSeq | MGI Sequence Detail 3079 C57BL/6  
polypeptide Q8BNL5 UniProt | EBI | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145760
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:197768 Lange S, et al., Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover. Mol Biol Cell. 2012 Jul;23(13):2490-504
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory