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Ccdc57 Gene Detail
Summary
  • Symbol
    Ccdc57
  • Name
    coiled-coil domain containing 57
  • Synonyms
    4933434G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918526
    NCBI Gene: 71276
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120717355-120823698 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.59 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918526
 protein coding gene Chr11:120717355-120823711 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019532
 protein coding gene Chr11:125333647-125445548 (-)
A/J MGP_AJ_G0019499
 protein coding gene Chr11:119738191-119845796 (-)
AKR/J MGP_AKRJ_G0019469
 protein coding gene Chr11:123359854-123474863 (-)
BALB/cJ MGP_BALBcJ_G0019474
 protein coding gene Chr11:120098252-120206293 (-)
C3H/HeJ MGP_C3HHeJ_G0019280
 protein coding gene Chr11:123686977-123798248 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019923
 protein coding gene Chr11:129133589-129251379 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017548
 protein coding gene Chr11:116727243-116834646 (-)
CAST/EiJ MGP_CASTEiJ_G0018834
 protein coding gene Chr11:125189294-125306753 (-)
CBA/J MGP_CBAJ_G0019251
 protein coding gene Chr11:134158264-134277149 (-)
DBA/2J MGP_DBA2J_G0019364
 protein coding gene Chr11:119111430-119221566 (-)
FVB/NJ MGP_FVBNJ_G0019355
 protein coding gene Chr11:118825498-118936927 (-)
LP/J MGP_LPJ_G0019435
 protein coding gene Chr11:125623164-125730276 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019388
 protein coding gene Chr11:132990501-133104447 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019962
 protein coding gene Chr11:124030045-124149588 (-)
PWK/PhJ MGP_PWKPhJ_G0018600
 protein coding gene Chr11:120549208-120659036 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018392
 protein coding gene Chr11:123791442-123905259 (-)
WSB/EiJ MGP_WSBEiJ_G0018887
 protein coding gene Chr11:124019426-124133089 (-)



Homology
more
  • Human Ortholog
    CCDC57, coiled-coil domain containing 57
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC57, coiled-coil domain containing 57
  • Links
    NCBI Gene ID: 284001
    neXtProt AC: NX_Q2TAC2
    UniProt: Q2TAC2

  • Chr Location
    17q25.3; chr17:82101460-82212878 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    22
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000048445 Ensembl Gene Model | MGI Sequence Detail 106344 C57BL/6J ±  kb
    transcript ENSMUST00000056781 Ensembl | MGI Sequence Detail 3403 Not Applicable  
    polypeptide ENSMUSP00000050996 Ensembl | MGI Sequence Detail 1016 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 22

      Microarray probesets 2
    References
    more
    • Summaries
      All 33
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:296121 Gurkaslar HK, et al., CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression. Cell Rep. 2020 May 12;31(6):107630
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/26/2023
    MGI 6.22     		The Jackson Laboratory