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Ccdc57 Gene Detail
Summary
  • Symbol
    Ccdc57
  • Name
    coiled-coil domain containing 57
  • Synonyms
    4933434G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918526
    NCBI Gene: 71276
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120717355-120823698 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.59 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2027 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918526
 protein coding gene Chr11:120717355-120823703 (-)
129S1/SvImJ ENSMUSG00200051745
 protein coding gene Chr11:118080870-118187266 (-)
A/J ENSMUSG00195024873
 protein coding gene Chr11:117755943-117862309 (-)
AKR/J ENSMUSG00220024339
 protein coding gene Chr11:117906331-118012698 (-)
BALB/cJ ENSMUSG00180045705
 protein coding gene Chr11:118048820-118155211 (-)
C3H/HeJ ENSMUSG00175043513
 protein coding gene Chr11:118006395-118112740 (-)
C57BL/6NJ ENSMUSG00215042121
 protein coding gene Chr11:117576424-117682782 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017548
 protein coding gene Chr11:116727243-116834646 (-)
CAST/EiJ ENSTCUG00005029793
 protein coding gene Chr11:117432275-117533679 (-)
CBA/J ENSMUSG00210046567
 protein coding gene Chr11:117720429-117826779 (-)
DBA/2J ENSMUSG00185026215
 protein coding gene Chr11:118033596-118139942 (-)
FVB/NJ ENSMUSG00205032019
 protein coding gene Chr11:117881278-117987646 (-)
JF1/MsJ ENSUMUG00000023662
 protein coding gene Chr11:118323145-118425109 (-)
LP/J ENSMUSG00230045987
 protein coding gene Chr11:119099929-119206320 (-)
NOD/ShiLtJ ENSMUSG00190044533
 protein coding gene Chr11:118104810-118211163 (-)
NZO/HlLtJ ENSMUSG00225049893
 protein coding gene Chr11:121248668-121355039 (-)
PWK/PhJ ENSLUMG00010023750
 protein coding gene Chr11:117841759-117944204 (-)
SPRET/EiJ ENSMSPG00010037062
 protein coding gene Chr11:118412123-118514189 (-)
WSB/EiJ ENSIUOG00005040002
 protein coding gene Chr11:117838009-117950730 (-)



Homology
more
  • Human Ortholog
    CCDC57, coiled-coil domain containing 57
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC57, coiled-coil domain containing 57
  • Links
    NCBI Gene ID: 284001
    UniProt: Q2TAC2

  • Chr Location
    17q25.3; chr17:82101459-82212878 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    22
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000048445 Ensembl Gene Model | MGI Sequence Detail 106344 C57BL/6J ±  kb
    transcript ENSMUST00000056781 Ensembl | MGI Sequence Detail 3403 Not Applicable  
    polypeptide ENSMUSP00000050996 Ensembl | MGI Sequence Detail 1016 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 22

      Microarray probesets 2
    References
    more
    • Summaries
      All 40
      Gene Ontology 7
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:358923 Pan X, et al., Directional ciliary beats across epithelia require Ccdc57-mediated coupling between axonemal orientation and basal body polarity. Nat Commun. 2024 Nov 26;15(1):10249
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory