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Lrrfip2 Gene Detail
Summary
  • Symbol
    Lrrfip2
  • Name
    leucine rich repeat (in FLII) interacting protein 2
  • Synonyms
    5133400F20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918518
    NCBI Gene: 71268
  • Alliance
    genome feature page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110946660-111054736 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.92 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2517 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918518
 protein coding gene Chr9:110946614-111054736 (+)
129S1/SvImJ ENSMUSG00200038383
 protein coding gene Chr9:108034320-108144192 (+)
A/J ENSMUSG00195035819
 protein coding gene Chr9:107327153-107441664 (+)
AKR/J ENSMUSG00220022464
 protein coding gene Chr9:107662569-107777081 (+)
BALB/cJ ENSMUSG00180027936
 protein coding gene Chr9:107781814-107896325 (+)
C3H/HeJ ENSMUSG00175029232
 protein coding gene Chr9:107997615-108112125 (+)
C57BL/6NJ ENSMUSG00215035206
 protein coding gene Chr9:107884435-107992516 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032754
 protein coding gene Chr9:106393766-106501852 (+)
CAST/EiJ ENSTCUG00005022993
 protein coding gene Chr9:107689612-107798182 (+)
CBA/J ENSMUSG00210028139
 protein coding gene Chr9:107720791-107830670 (+)
DBA/2J ENSMUSG00185037882
 protein coding gene Chr9:108045530-108160034 (+)
FVB/NJ ENSMUSG00205023009
 protein coding gene Chr9:107993636-108108142 (+)
JF1/MsJ ENSUMUG00000034924
 protein coding gene Chr9:107821771-107931657 (+)
LP/J ENSMUSG00230048658
 protein coding gene Chr9:108166416-108276276 (+)
NOD/ShiLtJ ENSMUSG00190043859
 protein coding gene Chr9:107633209-107747708 (+)
NZO/HlLtJ ENSMUSG00225023563
 protein coding gene Chr9:108423795-108531855 (+)
PWK/PhJ ENSLUMG00010026746
 protein coding gene Chr9:107828316-107938226 (+)
SPRET/EiJ ENSMSPG00010045224
 protein coding gene Chr9:109620019-109725361 (+)
WSB/EiJ ENSIUOG00005043550
 protein coding gene Chr9:107087313-107195357 (+)



Homology
more
  • Human Ortholog
    LRRFIP2, LRR binding FLII interacting protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRFIP2, LRR binding FLII interacting protein 2
  • Synonyms
    HUFI-2
  • Links
    NCBI Gene ID: 9209
    UniProt: Q9Y608

  • Chr Location
    3p22.2; chr3:37052626-37183689 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    628
  • Tissues
    8
  • cDNA Data
    78
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032497 Ensembl Gene Model | MGI Sequence Detail 108077 C57BL/6J ±  kb
transcript ENSMUST00000239186 Ensembl | MGI Sequence Detail 2421 Not Applicable  
polypeptide ENSMUSP00000159250 Ensembl | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    13 Sequences
  • Protein Ontology
    PR:000009943 leucine-rich repeat flightless-interacting protein 2
    (term hierarchy)
  • InterPro Domains
    IPR019139 Leucine-rich repeat flightless-interacting protein 1/2
  • GlyGen
    Q91WK0 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 79
    cDNA 78
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143149
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:297684 Hooper JE, et al., An Alternative Splicing Program for Mouse Craniofacial Development. Front Physiol. 2020;11:1099
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory