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Flacc1 Gene Detail
Summary
  • Symbol
    Flacc1
  • Name
    flagellum associated containing coiled-coil domains 1
  • Synonyms
    4933405P16Rik, 4933425F06Rik, Als2cr12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918359
    NCBI Gene: 108812
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:58696085-58735167 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 29.15 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1322 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918359
protein coding gene Chr1:58686062-58735167 (-)
129S1/SvImJ ENSMUSG00200018496
protein coding gene Chr1:56189652-56238748 (-)
A/J ENSMUSG00195025978
protein coding gene Chr1:55722883-55771975 (-)
AKR/J ENSMUSG00220038535
protein coding gene Chr1:55813058-55862153 (-)
BALB/cJ ENSMUSG00180013948
protein coding gene Chr1:55970726-56019819 (-)
C3H/HeJ ENSMUSG00175000914
protein coding gene Chr1:56100382-56149472 (-)
C57BL/6NJ ENSMUSG00215023343
protein coding gene Chr1:56032170-56081264 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005012492
protein coding gene Chr1:55886172-55921019 (-)
CBA/J ENSMUSG00210031359
protein coding gene Chr1:55796457-55834359 (-)
DBA/2J ENSMUSG00185054442
protein coding gene Chr1:56916149-56954049 (-)
FVB/NJ ENSMUSG00205017235
protein coding gene Chr1:55746202-55795290 (-)
JF1/MsJ ENSUMUG00000036081
protein coding gene Chr1:55877078-55911793 (-)
LP/J ENSMUSG00230024345
protein coding gene Chr1:56910209-56959308 (-)
NOD/ShiLtJ ENSMUSG00190032332
protein coding gene Chr1:55951887-56000978 (-)
NZO/HlLtJ ENSMUSG00225007594
protein coding gene Chr1:60124473-60161668 (-)
PWK/PhJ ENSLUMG00010023773
protein coding gene Chr1:55410935-55445908 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005019991
protein coding gene Chr1:55576893-55625985 (-)



Homology
more
  • Human Ortholog
    FLACC1, flagellum associated containing coiled-coil domains 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FLACC1, flagellum associated containing coiled-coil domains 1
  • Synonyms
    ALS2CR12
  • Links
    NCBI Gene ID: 130540
    UniProt: Q96Q35

  • Chr Location
    2q33.1; chr2:201288271-201364289 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit normal reproduction.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 108812 NCBI Gene Model | MGI Sequence Detail 39083 C57BL/6J ±  kb
transcript NM_001347056 RefSeq | MGI Sequence Detail 2747 C57BL/6  
polypeptide Q8BVM7 UniProt | EBI | MGI Sequence Detail 383 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000003974 flagellum-associated coiled-coil domain-containing protein 1
  • InterPro Domains
    IPR026674 Flagellum-associated coiled-coil domain-containing protein 1
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
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MGI:1921656, MGI:6285795
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:298518 Chotiner JY, et al., FLACC1 is testis-specific but dispensable for fertility in mice. Mol Reprod Dev. 2020 Nov 6;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory