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Trp53rka Gene Detail
Summary
  • Symbol
    Trp53rka
  • Name
    transformation related protein 53 regulating kinase A
  • Synonyms
    2810408M09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918294
    NCBI Gene: 381406
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:165332032-165335244 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.64 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918294
protein coding gene Chr2:165332030-165335244 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026895
protein coding gene Chr2:171055729-171059358 (-)
A/J MGP_AJ_G0026869
protein coding gene Chr2:165393304-165396260 (+)
AKR/J MGP_AKRJ_G0026833
protein coding gene Chr2:168937400-168941650 (-)
BALB/cJ MGP_BALBcJ_G0026878
protein coding gene Chr2:165744655-165746841 (+)
C3H/HeJ MGP_C3HHeJ_G0026613
protein coding gene Chr2:169284120-169287553 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027318
protein coding gene Chr2:176003580-176009741 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024689
protein coding gene Chr2:157446326-157449703 (-)
CAST/EiJ MGP_CASTEiJ_G0026071
protein coding gene Chr2:169716264-169722979 (-)
CBA/J MGP_CBAJ_G0026590
protein coding gene Chr2:182404565-182411059 (-)
DBA/2J MGP_DBA2J_G0026735
protein coding gene Chr2:164524613-164527391 (+)
FVB/NJ MGP_FVBNJ_G0026694
protein coding gene Chr2:161645702-161649797 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0026713
protein coding gene Chr2:185925893-185932177 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027382
protein coding gene Chr2:170214768-170218050 (+)
PWK/PhJ MGP_PWKPhJ_G0025815
protein coding gene Chr2:164159831-164162966 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025609
protein coding gene Chr2:167747023-167750525 (-)
WSB/EiJ MGP_WSBEiJ_G0026151
protein coding gene Chr2:171124692-171130414 (+)



Homology
more
  • Human Ortholog
    TP53RK, TP53 regulating kinase
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TP53RK, TP53 regulating kinase
  • Synonyms
    BUD32, C20orf64, dJ101A2, GAMOS4, Nori-2, Nori-2p, PRPK, TPRKB
  • Links
    NCBI Gene ID: 112858
    neXtProt AC: NX_Q96S44
    UniProt: Q96S44

  • Chr Location
    20q13.12; chr20:46684365-46689444 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human TP53RK associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 381406 NCBI Gene Model | MGI Sequence Detail 3213 C57BL/6J ±  kb
transcript NM_001007581 RefSeq | MGI Sequence Detail 1878 C57BL/6  
polypeptide NP_001007582 RefSeq | MGI Sequence Detail 244 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:141291 Tamplin OJ, et al., Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory