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Jhy Gene Detail
Summary
  • Symbol
    Jhy
  • Name
    junctional cadherin complex regulator
  • Synonyms
    4931429I11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918239
    NCBI Gene: 70989
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:40806145-40875414 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 21.68 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1763 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918239
 protein coding gene Chr9:40806145-40877560 (-)
129S1/SvImJ ENSMUSG00200038182
 protein coding gene Chr9:37885786-37948596 (-)
A/J ENSMUSG00195048226
 protein coding gene Chr9:37642685-37705505 (-)
AKR/J ENSMUSG00220044994
 protein coding gene Chr9:37724430-37787217 (-)
BALB/cJ ENSMUSG00180039307
 protein coding gene Chr9:37765935-37828770 (-)
C3H/HeJ ENSMUSG00175044315
 protein coding gene Chr9:37766483-37829284 (-)
C57BL/6NJ ENSMUSG00215021842
 protein coding gene Chr9:37723615-37792808 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032079
 protein coding gene Chr9:37760832-37825825 (-)
CAST/EiJ ENSTCUG00005043597
 protein coding gene Chr9:37704013-37766822 (-)
CBA/J ENSMUSG00210042217
 protein coding gene Chr9:37813472-37876282 (-)
DBA/2J ENSMUSG00185036992
 protein coding gene Chr9:37862285-37925076 (-)
FVB/NJ ENSMUSG00205039962
 protein coding gene Chr9:38129451-38192242 (-)
JF1/MsJ ENSUMUG00000042438
 protein coding gene Chr9:37914330-37983761 (-)
LP/J ENSMUSG00230033325
 protein coding gene Chr9:38174915-38238163 (-)
NOD/ShiLtJ ENSMUSG00190025539
 protein coding gene Chr9:37947547-38010331 (-)
NZO/HlLtJ ENSMUSG00225018936
 protein coding gene Chr9:38143400-38206651 (-)
PWK/PhJ ENSLUMG00010044460
 protein coding gene Chr9:37881904-37944546 (-)
SPRET/EiJ ENSMSPG00010032964
 protein coding gene Chr9:38600875-38663255 (-)
WSB/EiJ ENSIUOG00005037444
 protein coding gene Chr9:37370009-37432795 (-)



Homology
more
  • Human Ortholog
    JHY, junctional cadherin complex regulator
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    JHY, junctional cadherin complex regulator
  • Synonyms
    C11orf63
  • Links
    NCBI Gene ID: 79864
    UniProt: Q6NUN7

  • Chr Location
    11q24.1; chr11:122882683-122963865 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit hydrocephalus, domed cranium, ataxia, weight loss, enlarged lateral ventricle, neuodegeneration, abnormal brain ependymal motile cilium and premature death.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    2
  • cDNA Data
    4
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032023 Ensembl Gene Model | MGI Sequence Detail 69270 C57BL/6J ±  kb
    transcript ENSMUST00000034521 Ensembl | MGI Sequence Detail 3074 Not Applicable  
    polypeptide ENSMUSP00000034521 Ensembl | MGI Sequence Detail 770 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2143374
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:253677 Muniz-Talavera H, et al., The mouse Jhy gene regulates ependymal cell differentiation and ciliogenesis. PLoS One. 2017;12(12):e0184957
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory