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Trim45 Gene Detail
Summary
  • Symbol
    Trim45
  • Name
    tripartite motif-containing 45
  • Synonyms
    4921530N01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918187
    NCBI Gene: 229644
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:100829518-100844236 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 43.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    77 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918187
 protein coding gene Chr3:100828516-100844241 (+)
129S1/SvImJ ENSMUSG00200042148
 protein coding gene Chr3:97434264-97448983 (+)
A/J ENSMUSG00195041829
 protein coding gene Chr3:97840072-97854809 (+)
AKR/J ENSMUSG00220036783
 protein coding gene Chr3:96200197-96214934 (+)
BALB/cJ ENSMUSG00180030754
 protein coding gene Chr3:97779680-97794418 (+)
C3H/HeJ ENSMUSG00175022618
 protein coding gene Chr3:97325928-97340665 (+)
C57BL/6NJ ENSMUSG00215025201
 protein coding gene Chr3:98091724-98106443 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025426
 protein coding gene Chr3:95039446-95054114 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210050336
 protein coding gene Chr3:97948114-97962851 (+)
DBA/2J ENSMUSG00185039265
 protein coding gene Chr3:98433080-98447807 (+)
FVB/NJ ENSMUSG00205014997
 protein coding gene Chr3:97011240-97025960 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230044832
 protein coding gene Chr3:100362926-100377644 (+)
NOD/ShiLtJ ENSMUSG00190028110
 protein coding gene Chr3:98620529-98635254 (+)
NZO/HlLtJ ENSMUSG00225019413
 protein coding gene Chr3:102813109-102827846 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010045210
 protein coding gene Chr3:97484354-97495335 (+)
WSB/EiJ ENSIUOG00005030758
 protein coding gene Chr3:97967436-97982103 (+)



Homology
more
  • Human Ortholog
    TRIM45, tripartite motif containing 45
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM45, tripartite motif containing 45
  • Synonyms
    RNF99
  • Links
    NCBI Gene ID: 80263
    UniProt: Q9H8W5

  • Chr Location
    1p13.1; chr1:117111060-117123927 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    666
  • Tissues
    34
  • cDNA Data
    22
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033233 Ensembl Gene Model | MGI Sequence Detail 14719 C57BL/6J ±  kb
    transcript ENSMUST00000134993 Ensembl | MGI Sequence Detail 2274 Not Applicable  
    polypeptide ENSMUSP00000115669 Ensembl | MGI Sequence Detail 757 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 22

      Microarray probesets 2
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 8
      Phenotypes 17
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory